Award Data

From HIV to metastatic cancer, state-of-the-art therapeutics are static biological or pharmaceutical compounds—whose efficacy is inevitably lost once their evolving disease targets sufficiently mutate. We engineered the first adaptive therapeutics designed to co-adapt with adapting disease agents—to provide ‘resistance-proof’ disease control. Known as Therapeutic Interfering Particles (‘ ...

We propose to continue our project generating transgenic insect with improved nutrition for humans and livestock, building on the milestones we have reached and will continue to develop in phase I. We have already demonstrated insertion of exogenous reporter DNA into the insect, and continue to develop genetic engineering tools and techniques. We have expressed the biosynthetic pathway of interest ...

Development of air vehicles capable of routine operation and able to achieve hypersonic speeds is paced by the availability of a propulsion system. The vision is to combine improved off-the-shelf turbines for low-speed operation (M=0 to 2+) and dual-mode ramjet (DMSJ) engine technologies for high-speed operation (M=2+ to 5+), with both engines sharing a common air inlet and a common thrust produci ...

During the phase I effort, Semandex Networks and its team designed and implemented a proof-of-concept cloud-based application for knowledge navigation and document discovery that combines powerful text analytics with an intuitive UI. The prototype capability is poised to transform current data archival systems into meaningful connected information. The proof-of-concept prototype developed during t ...

The objective of the proposed efforts is the development of a novel high energy reserve type lithium ion battery (LIB) based safe power source for gun-fired projectiles that can survive launch setback accelerations of up to 70,000 Gs and capable of providing power for weeks at very low temperatures as required for military operations. The proposed concepts also allow the development of highly safe ...

Having successfully validated our superhydrophobic, self-cleaning, wear and rust resistant laser based surface process in the Phase 1 project period, we at AlchLight propose to scale this technology to industry relevant levels by once again working with members of the University of Rochester's High Intensity Laser Lab. To achieve this goal, we will develop the world’s first superhydrophobic micr ...

To satisfy the demand for increased data volumes from small satellite systems, TUI proposes to extend its existing modular SWIFT software-defined radio (SDR) platform to create a multi-band S-, X-, and Ka-band transceiver capable of closing SATCOM links in excess of 300 Mbps to smaller, tactically-placed ground stations. Key enabling technologies include the integration TUI’s existing three degr ...

Unmanned ground vehicles are becoming widely seen as a means of increasing safety and production for a variety of purposes. These vehicles are used in a diverse range of applications (e.g. military, mining, agriculture, automotive). Many control parameters scale nicely with the size and type of vehicle. However, performance requirements also vary based on accuracy and smoothness of control per cus ...

Low cost polyurethane laminate tent materials are designed to solve the cold crack issue with PVC tent fabrics. The use of novel construction of urethane/textile laminates offers a breakthrough in environmental durability over current offerings. This new high durability laminate configuration provides for a new class of economical lightweight shelters with extended operating capability. Using a co ...

Maxentric’s solution provides multi-level security and information flow control with cell level encryption for existing relational databases. At the tactical edge, access to advanced cloud based services such Apache Accumulo may not be possible. The novel database solution allows these types of services to be deployed in any point of the network, but also to be integrated in already existing app ...