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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Synthetic Universal Flu Vaccine

    SBC: TRIA BIOSCIENCE CORP.            Topic: NCIRD

    Abstract Type A and B Influenza viruses cause severe seasonal epidemics and less frequent but more deadly pandemic infectionsVaccination provides the best protectionalthough serious problems are confronting the global Influenza marketVirus diversity and mutation rates necessitate the annual production of hundreds of millions of vaccines using antiquated egg based technologiesCompounding this is th ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  2. Engineering Nanoparticle Alum Adjuvants for Pandemic Influenza Vaccines

    SBC: HDT BIO CORP            Topic: NCIRD

    Project Summary SignificanceSinceavian influenza AH Nhas sickened overpeople with amortality rateHalf of all cases occurred inwhich also saw the emergence of a highly pathogenic strainThusH Navian influenza is poised to emerge as a devastating pandemic in a worldwide population that has no pre existing immunityCurrent Hvaccineswhether attenuatedinactivatedsplit or recombinantare insufficiently imm ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  3. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  4. Generation of Tissue Engineered Nerve Grafts from GalSafe Porcine Neurons

    SBC: Axonova Medical LLC            Topic: NINDS

    ABSTRACT Peripheral nerve injuryPNIis a common consequence of trauma or surgeryand the extent of functional recovery is often unsatisfactoryMoreovera particular challenge is the repair ofmajorPNIdefined as injuries where a large segment of a nerve is losti eandgtcmor more proximal injuriese gbrachial plexus or upper armthat necessitate extremely long distances for axonal regeneration to distal end ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A Rapid Multiplexed Assay for the Diagnosis of Viral Hepatitis at the Point of Care

    SBC: INSTADIAGNOSTICS INC            Topic: NCHHSTP

    Abstract InstadiagnosticsIDIis developing a point of carePOCdiagnostic technology platform with the goal of providing early detectionscreeningand treatment monitoring for patients at primary care centerscommunity clinicsurgent care centersand emergency departmentsThe device consists of a portable readerthe InstaReaderand disposable cartridgesInstaCartridgeA range of disease specific cartridges wil ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. Linkage-specific ubiquitylation patterns as highly sensitive markers for neurodegenerative disease

    SBC: LIFESENSORS, INC.            Topic: NIA

    While sensitive imaging tools to detectamyloid and tau proteins and other biomarkers for established Alzheimer s diseaseADand other neurodegenerative diseases are availablesimilar tools for detecting presymptomaticetiologic biomarkers of these diseases are notAmong the earliest steps in AD is a failure of the ubiquitin proteasome pathway to respond to misfolded proteins by causing their degradatio ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Mechanism of action of oligomer-displacing Alzheimer investigation drug, CT1812:Receptor interactions and signaling pathways

    SBC: COGNITION THERAPEUTICS, INC.            Topic: NIA

    Abstract Aoligomers are considered the most toxic structural form of Amyloid betacausing synaptotoxic changes underlying cognitive decline in Alzheimer s diseaseCogRx has developed the world s first highly brain penetrant drug that selectively displaces oligomers from synaptic receptor sites and clears oligomers from the brain into the cerebrospinal fluidCSFThis first in class drugCTallosterically ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. MyHealthyPregnancy mobile health app: Combining behavioral science and machine learning for risk communication during the peripartum period

    SBC: Naima Health LLC            Topic: NCCDPHP

    Project Summary Abstract BackgroundPreterm birthsthose that occur prior toweeks of gestationare the leading direct cause of neonatal mortality and morbidityMore thaninbirths in the U Sare pretermwith rates that are disproportionately high among African Americans and families living in povertyregardless of raceAddressing the problem of preterm birth requires both accurate identification of the fact ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  9. A Noninvasive Platform to Assess Maternal Risk for Perinatal Complications in the First Trimester

    SBC: Cradle Genomics, Inc.            Topic: NICHD

    Limited information is available about early human placentation when many pregnancy pathologies originateTo address this knowledge gap and begin development of robust diagnostic tool to manage pregnancy complicationswe propose a pilot study based on a highly sensitive immune assay and our company s base technologyTrophoblast Retrieval and Isolation from the CervixTRICTRIC uses a Pap smearconsidere ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. High-throughput nanoMEA-based Proarrhythmia Assay

    SBC: CURI BIO, INC.            Topic: NHLBI

    PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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