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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Prehospital and Emergency Room Stroke Diagnosis Using Quantitative Cerebral Hemodynamics

    SBC: Neural Analytics, Inc.            Topic: NINDS

    Large vessel acute ischemic strokeAISis the leading cause of disability and fourth leading cause of death with approximatelyper year in the United States aloneAlthough treatments including interventionalstentrieverand pharmaceuticaltPAexist for large vessel occlusionLVOthere is not a rapid prehospital tool for diagnoses which guides the use of the correct therapyBecause the time to treatment for s ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A Clothing-Adhered Wearable to Monitor Biomarkers of Cognitive/Emotional State and Deliver Just-in-Time Behavioral Interventions

    SBC: Spire, Inc.            Topic: NIDA

    PROJECT SUMMARY Recovery from substance use disorders (SUDs) is greatly impacted by the cognitive and emotional state of the individual, and learning new thought and behavioral patterns can facilitate successful treatment and recovery. Specifically, fluctuations in stress or anxiety can trigger lapses to drug use. Even when actual use is avoided, stress-induced craving is likely to be distracting ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel, Low-Cost Device to Guide Peripherally Inserted Central Catheter (PICC) Line Placement

    SBC: Theranova LLC            Topic: NIA

    Abstract Improper placement of peripherally inserted central cathetersPICCsis costly and has serious complications for critically ill patientsMore than one million PICCs are placed each year to provide IV therapieswhere navigation through the venous system is typically performed blindor without navigation guidanceAs a resultof PICC tips are not optimally placed on the first attempt and require rep ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Preclinical Development of Oxy200 for the Treatment of Osteoporosis

    SBC: Max Biopharma, Inc.            Topic: NIA

    ABSTRACT Osteoporosis directly affectsmillion Americans and anothermillion are osteopenic and at risk for developing osteoporosisPostmenopausal osteoporosis is most commonbut osteoporosis does also frequently affect older menAt MAX BioPharmawe are developing new and improved therapies for osteoporosis that aim to rebalance both bone formation and resorption based on a dual therapy approachBisphosp ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. AD-MS Chips for Biofluids-Based Diagnosis of Alzheimer's Disease

    SBC: NEWOMICS INC.            Topic: NIA

    Project Summary Abstract Alzheimerandapos s diseaseADis a devastating neurodegenerative disease that affects more thanmillion peopleincludingmillion Americansworldwideand this number is expected to reach more thanmillion by the yearRecent disappointing results from a large number of clinical trials for AD treatment further aggravate the problemOne major challenge is there is currently no blood bas ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. IND-enabling studies on novel Cav3 T-channel modulators for treatment of neuropathic pain

    SBC: AFASCI, INC.            Topic: NINDS

    7. PROJECT SUMMARY Neuropathic pain remains a poorly managed medical condition affecting more than 1.5 billion people worldwide. Over 20 million people suffered from diabetic neuropathy and neuropathic pain in the US alone in 2015. The current standard of care is insufficient. Topical applications and systemic treatment with existing analgesics, including opioids, leave millions suffering. More th ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Sustained release of next-generation aptamers to treat wet AMD

    SBC: APTITUDE MEDICAL SYSTEMS INC            Topic: NEI

    Abstract SignificanceWet AMD affectsM Americans and is the leading cause of blindness in those agedor olderVision improvement from anti VEGF treatment is neither permanent nor completeand patients must receive intravitreal injections everymonthscreating a major treatment burden for patientsphysicians and payersEmerging combination therapies could address the efficacy problembut they do not solve t ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. EXTENDING INDEPENDENCE AND QUALITY OF LIFE FOR PEOPLE WITH ALZHEIMER'S DISEASE OR DEMENTIA THROUGH TELEHEALTH PROGRAM DELIVERY

    SBC: Together Senior Health, Inc.            Topic: NIA

    Project Abstract More thanmillion Americans are living with Alzheimer s disease or dementiaplacing an enormous cost and service burden on the medical system and often imposing devastating quality of life challenges on patients and their caregiversCurrent medications are minimally effective in delaying the multiple functionalcognitiveand behavioral factors that lead specifically to decline in quali ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Senescence After Growth Arrest a new therapeutic modality for progeria

    SBC: Atropos Therapeutics, Inc.            Topic: NIA

    Abstract The long term goal of Atropos Therapeutics Incis development of a therapeutic drug for progeria and other aging related disorders based on their ability to regulate the senescence processAt the end of PhaseSBIRwe anticipate having two to five scaffolds that have utility slowing or preventing cellular senescence in tissue cultureIn phasewe anticipate moving scaffolds toward lead selectiont ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Computerized tests of cognitive decline in presymptomatic Alzheimer's disease

    SBC: NEUROBEHAVIORAL SYSTEMS INC            Topic: NIA

    Patients who develop Alzheimer s diseaseADshow performance declines in tests of episodic memoryexecutive functioningand attention more than a decade before symptoms become apparent to their physician or familyThe rate of this performance decline is the primary outcome measure in ongoing clinical trials evaluating interventions aimed at delaying AD onsetHowevercurrent clinical trials rely on measur ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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