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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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High-throughput nanoMEA-based Proarrhythmia Assay
SBC: CURI BIO, INC. Topic: NHLBIPROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Non-surgical treatment option for pelvic organ prolapse
SBC: REIA LLC Topic: NICHDProject SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia
SBC: Cascade Biotechnology Topic: NHLBIAbstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Smart Cavity Creator Drill for Lumbar Interbody Fusion
SBC: PEER Technologies PLLC Topic: NIBIBPROJECT SUMMARYABSTRACT Older patients with persistent and progressive symptoms of chronic back pain and leg pain often have a diagnosis of lumbar degenerative spondyolisthesis and undergo complex lumbar decompression and fusion surgeryOverof these procedures are performed in the United States each yearSurgery is highly effective but technically challengingOne technical challenge of fusion in spon ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Transforming STEM Education in K-12 using the Biological Interactive Outcomes Modular Environment (BIOME)
SBC: IQ Smart Interactive LLC Topic: 500PROJECT SUMMARYThe United States is falling behind in Science and Math according to results from the Programme for International Student AssessmentPISAranking the US asth in Science andth in Mathematics out ofcountriesThese unfortunate statistics could be attributed to teacher hesitations in teaching math and scienceinability to excite student interest in STEM subjectsor an unclear real world appl ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
STEM Interactive Digital Tool to Educate and Promote Hearing Health and Science for 4th to 7th Grade
SBC: CREARE LLC Topic: 500PROJECT SUMMARY ABSTRACT The National Research Council recognizes that serious computer games can support new inquiry based approaches to science instructionproviding virtual laboratories or field learning experiences that overcome practical and logistical constraints to student investigationsWith the nationally recognized need to encourage and enhance education in the ScienceTechnologyEngineering ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Interstitial Intensity Modulated Photodynamic Therapy Phase II
SBC: SIMPHOTEK, INC. Topic: 102Photodynamic therapy (PDT) is a cancer treatment that utilizes visible or near-infrared light to activate a light- sensitive drug (photosensitizer, PS) that, in turn, creates reactive singlet oxygen species from ground triplet state oxygen that is present in the tumor. The resulting reactive products induce tissue death. Ideally the reactive species will be produced within only the target volume, ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development and Validation of a Platform to Assess and Improve Barriers to Health for Digitally Underserved Populations
SBC: Responsive Health, Inc. Topic: 102Project SummaryInflammatory bowel diseaseIBDis a chronic disabling disease that leads to poor quality of life among otherwise young healthy adultsUnderserved and minority populations bear a higher disease burden with more hospitalizations and less use of gastroenterology specialty care and of maintenance medications to prevent flaresThe goal of this proposalDevelopment and Validation of a Platform ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a PSMA-Targeted Small-Molecule Drug Conjugate for Prostate Cancer
SBC: Cancer Targeted Technology LLC Topic: 102PROJECT SUMMARY ABSTRACTProstate Specific Membrane AntigenPSMAis an andapos ideal biomarkerandaposfor tumor targeting as it exhibits restricted expression on prostate tumor cells and the neovasculature of a number of other solid tumorsCancer Targeted Technology has developed unique phosphoramidate based PSMA inhibitor scaffolds that irreversibly bind to the enzyme target and selectively penetrate ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
TrachAlarm: A novel, low-cost accessory to automatically detect and alert caregivers to tracheostomy tube decannulation
SBC: INNOVATIONS UNLIMITED LLC Topic: NINRABSTRACT The objective of the Phasegrant is to designdevelopand demonstrate feasibility of TrachAlarma novellow cost accessory to automatically detect and alert caregivers when a tracheostomy tube has become accidentally removed from the patientTracheostomy provides a criticallife supporting function for overmillion individuals in the United States with overnew procedures performed each yearEach o ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health