Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Synthetic Universal Flu Vaccine

    SBC: TRIA BIOSCIENCE CORP.            Topic: NCIRD

    Abstract Type A and B Influenza viruses cause severe seasonal epidemics and less frequent but more deadly pandemic infectionsVaccination provides the best protectionalthough serious problems are confronting the global Influenza marketVirus diversity and mutation rates necessitate the annual production of hundreds of millions of vaccines using antiquated egg based technologiesCompounding this is th ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Engineering Nanoparticle Alum Adjuvants for Pandemic Influenza Vaccines

    SBC: HDT Bio Corp.            Topic: NCIRD

    Project Summary SignificanceSinceavian influenza AH Nhas sickened overpeople with amortality rateHalf of all cases occurred inwhich also saw the emergence of a highly pathogenic strainThusH Navian influenza is poised to emerge as a devastating pandemic in a worldwide population that has no pre existing immunityCurrent Hvaccineswhether attenuatedinactivatedsplit or recombinantare insufficiently imm ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Non-surgical treatment option for pelvic organ prolapse

    SBC: Reia, LLC            Topic: NICHD

    Project SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Development and evaluation of an internet based adaptation of the New Beginnings Program for divorced parents

    SBC: Family Transitions- Programs that Work, LLC            Topic: NICHD

    PROJECT ABSTRACT The proposed research builds on a successful Phase I SBIR grant to develop and test a web based version of a parenting after divorce group interventionthe New Beginnings Programwhich has been shown in two randomized trials to reduce youthsproblem behaviors and enhance their developmental competencies in theyear period after their parents participatedThe proposed web based format w ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. High-throughput nanoMEA-based Proarrhythmia Assay

    SBC: Nanosurface Biomedical, Inc.            Topic: NHLBI

    PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Novel radiometry-guided ablation catheter to treat resistant hypertension or CKD

    SBC: Symple Surgical Inc            Topic: R

    PROJECT SUMMARY Increased renal sympathetic activity is a causal pathogenetic mechanism of both cardiovascular hypertension and progressive loss of renal function in patients with chronic kidney diseaseCKDIn millions of patients with resistant hypertensiondependable thermal disruption of targeted renal sympathetic nerves can reduce blood pressure and ultimately prevent heart diseasestroke and kidn ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. 4D Acoustoelectric Cardiac Imaging for Fast and Accurate Mapping of Arrhythmias

    SBC: ElectroSonix LC            Topic: NHLBI

    Abstract Despite global success of interventional cardiac surgery for treatment of arrhythmiaselectroanatomical mappingEAMof the heart has significant drawbacksThe procedure is slow and prone to registration errorslargely ineffective for treating transient arrhythmiassuch as ventricular tachycardiaand exhibits relatively poor spatial resolutionWith only asuccess rate for first time interventionsth ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Automated Contingency Management System for Reduction of Alcohol Use

    SBC: Managed Health Connections LLC            Topic: 450

    Project Summary Abstract Alcohol abuse remains a significant cause of preventable morbidity and mortality in the USYet onlyof those with AUD receive treatmentOur groupand others have demonstrated that contingency managementCMis an effective approach for reducing alcohol use in problematic drinkersThis project seeks to demonstrate the capability of an end to end CM platform designed to reduce alcoh ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Highly Sensitive Chimerism Testing to Detect Early Leukemia Relapse Post-Allo-Transplantation

    SBC: Chimerocyte, Inc.            Topic: 102

    ABST RACT Patients with acute blood malignancies who undergo allogeneic hematopoietic stem cell transplantationHSCTare monitored for minimal residual diseaseMRDas predictive of relapseIncreasing mixed chimerismreemerging recipient cellscorrelates with reappearance of underlying disease by association with MRDGenetic and immunophenotypic heterogeneity of these malignancies often prevents establishi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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