Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A Phase 1 Clinical Trial Evaluating the Novel Small Molecule Immuno-Oncology Antagonist SX-682 Alone and With Pembrolizumab in Metastatic Melanoma

    SBC: Syntrix Biosystems, Inc.            Topic: 102

    The chemokine receptors CXCRand CXCRCXCRare validated as having essential roles in the growthsurvivalmotilityinvasion and angiogenesis of human melanomawhich secretes abundant amounts of the corresponding chemokine ligandsincluding CXCLAdditionallyabnormal cancer induced immunosuppressive myeloid derived suppressor cellsMDSCsin the circulation and tumor correlate with melanoma stagemetastatic tumo ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. A cooling guide catheter for rapid heart cooling

    SBC: FOCALCOOL, LLC            Topic: N/A

    Location FOCALCOOL, LLC 25 LYNNFIELD DR 08520 EAST WINDSOR, NJ United States 40° 15' 57.1932" N, 74° 32' 4.596" W New Jersey US 2R44HL088789-02A1 $939 644.00 2 008 A cooling guide catheter for rapid heart cooling Department of Health a ...

    SBIR Phase II 2008 Department of Health and Human Services
  3. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. ADEPT GIS: ALCOHOL AND DRUG EPIDEMIOLOGY and TREATMENT GEOGRAPHIC INFORMATION SERVI

    SBC: LOOKING GLASS ANALYTICS, INC.            Topic: N/A

    This proposal describes enhancements to the ADEpT GIS, an internet-based software application that allows users to generate statistical analyses, maps, and reports on community-level measures of substance abuse. This web service augments the work of groups like the NIDA-sponsored Community Epidemiological Workgroups by providing a data repository and accessible analysis system for reporting and su ...

    SBIR Phase II 2008 Department of Health and Human Services
  5. A Device to Monitor Toe Walking in Children with Cerebral Palsy

    SBC: Simbex LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This goal of this SBIR project is to quantify and validate the feasibility and potential for a non- obtrusive, wearable, in-shoe gait-monitoring device for children with Cerebral Palsy (CP). It is hypothesized that continuous monitoring and analysis of simple gait parameters in children with CP outside the clinical laboratory and during normal daily activities ...

    SBIR Phase II 2008 Department of Health and Human Services
  6. An Automated Early Motor Development Risk Screener from Observational Video Recordings of Infants and Toddlers

    SBC: BSolutions Inc            Topic: NICHD

    Motor development plays a pivotal role in an infant s overall development and has a cascading effect on socialcognitivememoryand language abilityThese functions can be compromised when motor development is disruptedmotor disruption is associated with generalized developmental delaysEarly screening and identification of delays can allow early interventions with the goal of not just improving motor ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. An anti-CD74 MAb-drug conjugate for B-cell malignancies

    SBC: IMMUNOMEDICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this work is to develop an antibody-doxorubicin conjugate for the targeted therapy of B-cell cancers that express the CD74 antigen. The Phase II project will focus on advancing this product for multiple myel oma, a common plasma cell malignancy that is incurable at this time. The average 5-year survival rate for these patients is only 30%, and there ...

    SBIR Phase II 2008 Department of Health and Human Services
  8. Augmented Reality Sensor Simulation System for HAZMAT Training

    SBC: CELL PODIUM LLC            Topic: 142

    Summary AbstractAugmented Reality HAZMAT Sensor Simulator Phase II A goal of HAZMAT training exercises is to present learners with realistic tasks and experiences involving mock hazardsprotective equipmentPPEtoolsand hazard sensorsHoweverwhile mock hazardsPPEand tools are readily available to trainerssensors that operate with mock hazards are notBecause the decisions that a HAZMAT worker makes are ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. CAMS Relational Agent System (CAMS-RAS) for Suicide Prevention

    SBC: EVIDENCE-BASED PRACTICE INSTITUTE, INC.            Topic: 104

    PROJECT ABSTRACTOverpeople die annually by suicide in the United StatesUSmaking suicide theth leading cause of death overall and the second leading cause of death among thoseIn additionmillion adults contemplate suicide annuallyand one million will make a suicide attemptFromtothe rate of ED visits for suicidal ideation among adults increased byon average annuallyWhile millions are devoted annually ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Co-located Earphone/Microphone for Active Noise Reduction

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is to design, fabricate, and test co-located earphones/microphones for use in in- ear, active noise reduction (ANR) systems. Our innovation is based on a micromachined membrane that serves as both the sensing element for a microphone and simultaneously the actuation surface for the earphone. By collocating the earphone and microph ...

    SBIR Phase II 2008 Department of Health and Human Services
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