Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development and evaluation of an internet based adaptation of the New Beginnings Program for divorced parents

    SBC: Family Transitions- Programs that Work, LLC            Topic: NICHD

    PROJECT ABSTRACT The proposed research builds on a successful Phase I SBIR grant to develop and test a web based version of a parenting after divorce group interventionthe New Beginnings Programwhich has been shown in two randomized trials to reduce youthsproblem behaviors and enhance their developmental competencies in theyear period after their parents participatedThe proposed web based format w ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. High-throughput nanoMEA-based Proarrhythmia Assay

    SBC: Nanosurface Biomedical, Inc.            Topic: NHLBI

    PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. STEM Interactive Digital Tool to Educate and Promote Hearing Health and Science for 4th to 7th Grade

    SBC: CREARE LLC            Topic: 500

    PROJECT SUMMARY ABSTRACT The National Research Council recognizes that serious computer games can support new inquiry based approaches to science instructionproviding virtual laboratories or field learning experiences that overcome practical and logistical constraints to student investigationsWith the nationally recognized need to encourage and enhance education in the ScienceTechnologyEngineering ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Interstitial Intensity Modulated Photodynamic Therapy Phase II

    SBC: SIMPHOTEK, INC.            Topic: NCI

    Photodynamic therapyPDTis a cancer treatment that utilizes visible or near infrared light to activate a lightsensitive drugphotosensitizerPSthatin turncreates reactive singlet oxygen species from ground triplet state oxygen that is present in the tumorThe resulting reactive products induce tissue deathIdeally the reactive species will be produced within only the target volumeleading to damage of t ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Dual View Endoscopy for Colonoscopy

    SBC: Omniscient Imaging, Inc.            Topic: 102

    AbstractAn estimatedmillion colonoscopies are performed annually in the US at a cost of about $Bhowever current colonoscopes with forward vision fail to detectof precancerous polypsOverof the missed polyps are located on or behind numerous folds in the colon where they are hidden from the sight of a forward view colonoscopeIn this research proposalwe propose to complete our development of an imagi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Lab-To-Marketplace: Commercialization of a stretchable microelectrode array

    SBC: BMSEED LLC            Topic: 101

    Project Summary Abstract The proposed work is directed at the commercialization of BMSEEDandapos s Micro Electrode Array Stretching Stimulating und Recording EquipmentMEASSuREtechnologyMEASSuRE bridges the gap between in vitro and in vivo research by simulating the biomechanical and electrical environment of cells in the body in a controlled environment outside of the bodyThe applications for MEAS ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Complex 3-Dimensional in vitro Human Skin Tissue Models for Scleroderma

    SBC: CELDARA MEDICAL, LLC            Topic: NIAMS

    PROJECT SUMMARY Sclerodermasystemic sclerosisSScis an autoimmune disease of unknown etiology that is characterized by vascular dysfunctionfibrosisand inflammationOne in three patients dies withinyears of diagnosisgiving SSc the highest case fatality rate of any systemic autoimmune diseaseA lack of biologically relevant SSc disease models has created a critical unmet need for more efficient preclin ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Early Detection of Ovarian Cancer Using Uterine Lavage and Duplex Sequencing

    SBC: Twinstrand Biosciences, Inc.            Topic: 102

    TBD

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Sleeping Beauty Engineered B Cells for Mucopolysaccharidosis

    SBC: Immusoft Corporation            Topic: 300

    Project Summary Mucopolysaccharidosis type IMPS Iis an autosomal recessive storage disease caused by the absence ofL iduronidaseIDUAresulting in systemic accumulation of glycosaminoglycanGAGstorage materialshepatosplenomegalyskeletal dysplasiascardiopulmonary obstructionprogressive neurologic impairment and death by ageMPS I is currently treated by enzyme replacement therapy and by allogeneic hema ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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