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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Parameter Development for the Scaled Manufacturing of Mycelium Bound Panels for Commercial Interior Products

    SBC: ECOVATIVE DESIGN LLC            Topic: 16NCER6A

    Ecovative Design uses grown mycelium structures to bind agricultural and wood byproducts into inherently nontoxic_x000D_ products containing no added urea formaldehyde or flame-retardant chemicals. This research program focuses_x000D_ on maturing mycelium technology for use in the production of large scale board products, from low density (LD) particle board to acoustic panels and thermal insulati ...

    SBIR Phase II 2018 Environmental Protection Agency
  2. An Enhanced Contact Plasma Reactor: A Competitive Remediation Technology for Per- and Perfluoroalkyl Substance (PFAS) Contaminated Water

    SBC: Dmax Plasma LLC            Topic: 17NCER1A

    Perfluoroalkyl substances (PFASs) have received considerable attention due to their toxicity, ubiquitous presence and recalcitrance. Manufacture and disposal of PFAS-containing products has resulted in PFAS contamination of numerous water supplies. Recent reports indicate the Air Force alone is expecting to spend > $2.25 billion for cleanup for PFAS-contaminated sites. Thus, there is a huge market ...

    SBIR Phase I 2018 Environmental Protection Agency
  3. Green Process for Plastic Chrome

    SBC: VERGASON TECHNOLOGY, INC.            Topic: 17NCER5B

    This green approach to manufacturing plastic with decorative chrome will eliminate health and environmental hazards from the chrome electroplating process. The US and global market for decorative chrome on plastic is 12 million m2/year and 84 million m2/year respectively, with 80% in automobile trim, 10% in appliances and 10% in sanitary fixtures. Without a viable commercial alternative, US provid ...

    SBIR Phase I 2018 Environmental Protection Agency
  4. Enhanced Treatment Management of Opioid-Dependence in an Office-Based Setting

    SBC: MedicaSafe Inc            Topic: NIDA

    PROJECT SUMMARY ABSTRACT Opioid use disorder is the leading cause of accidental death in the USwith overlethal drug overdoses inSAMHSA estimates thatmillion Americans misuse prescription opioids for non medical purposes annuallyPublic health officials and policymakers have acknowledged the urgent need for innovative approaches to the treatment of those with opioid use disorderin spite of thisthe a ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Automated Assessment of Leptomeningeal Collaterals on CT Angiograms

    SBC: Kitware, Inc.            Topic: 108

    AbstractThe primary goal of this study is to develop an automated scoring system of leptomeningeal collaterals based on CT angiographyCTAas a quantitative assessment of acute ischemic strokeLeptomeningeal collaterals provide an alternate path of blood flow in the setting of a proximal vessel occlusionThe presence and effectiveness of leptomeningeal collateralsi ecollateral statusvaries significant ...

    STTR Phase II 2018 Department of Health and Human Services
  6. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Tau oligomer platform validation using lead series candidate in htau mice

    SBC: Oligomerix, Inc.            Topic: NIA

    TITLETau oligomer platform validation using lead series candidate in htau mice PROJECT SUMMARYSBIR Funding OpportunityAdvancing Research on Alzheimerandapos s DiseaseADand Alzheimerandapos s Disease Related DementiasADRDRRPASThe long term goal of this program is to develop a disease modifyingsmall molecule drug for Alzheimer s diseaseADand related tauopathiesThere is a critical unmet need for a di ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Gene and Stem Cell-Based Treatment for Tendinopathy

    SBC: NEW YORK R&D CENTER FOR TRANSLATIONAL MEDICINE AND THERAPEUTICS, INC.            Topic: R

    Project SummaryTendinopathy is a common chronic tendon disorder that affectsof individuals overyears oldIt is characterized by painswellingloss of functionand impaired performanceThere is currently no cure for tendinopathySpontaneous repair or treatment typically leads to scar formationresulting in a weakened tissue with reduced function and mechanical properties that may ultimately rupture with f ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Scale-up and Synthesis of a Tau Oligomer Inhibitor to initiate IND enabling studies for AD and ADRD

    SBC: Oligomerix, Inc.            Topic: NIA

    PROJECT SUMMARYSBIR RRFast Track ApplicationFOA NumberPASThe long term goal of this program is to develop a disease modifyingsmall molecule drug for Alzheimer s diseaseADand AD related dementiasADRDwith tau pathologyThere is a critical unmet need for a disease modifying drugDMDfor ADChronic treatment strategies require safeeffectiveand economically feasible approaches such as small molecule drugsT ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Development and validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 103

    Project Summary Sanfilippo diseasemucopolysaccharidosis type IIIMPS IIIis a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologicslowing of developmentsevere behavioral problemsprogressive cognitive declinedementiaand decline in motor skills leading to immobilityunresponsivenessand deathWe have focused on MPS IIID caused by a deficiency of a ...

    SBIR Phase II 2018 Department of Health and Human Services

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