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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High-throughput nanoMEA-based Proarrhythmia Assay

    SBC: CURI BIO, INC.            Topic: NHLBI

    PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. STEM Interactive Digital Tool to Educate and Promote Hearing Health and Science for 4th to 7th Grade

    SBC: CREARE LLC            Topic: 500

    PROJECT SUMMARY ABSTRACT The National Research Council recognizes that serious computer games can support new inquiry based approaches to science instructionproviding virtual laboratories or field learning experiences that overcome practical and logistical constraints to student investigationsWith the nationally recognized need to encourage and enhance education in the ScienceTechnologyEngineering ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Interstitial Intensity Modulated Photodynamic Therapy Phase II

    SBC: SIMPHOTEK, INC.            Topic: 102

    Photodynamic therapy (PDT) is a cancer treatment that utilizes visible or near-infrared light to activate a light- sensitive drug (photosensitizer, PS) that, in turn, creates reactive singlet oxygen species from ground triplet state oxygen that is present in the tumor. The resulting reactive products induce tissue death. Ideally the reactive species will be produced within only the target volume, ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Complex 3-Dimensional in vitro Human Skin Tissue Models for Scleroderma

    SBC: CELDARA MEDICAL, LLC            Topic: NIAMS

    PROJECT SUMMARY Sclerodermasystemic sclerosisSScis an autoimmune disease of unknown etiology that is characterized by vascular dysfunctionfibrosisand inflammationOne in three patients dies withinyears of diagnosisgiving SSc the highest case fatality rate of any systemic autoimmune diseaseA lack of biologically relevant SSc disease models has created a critical unmet need for more efficient preclin ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Early Detection of Ovarian Cancer Using Uterine Lavage and Duplex Sequencing

    SBC: TWINSTRAND BIOSCIENCES INC            Topic: 102

    Nearly a quarter of a million new cases of ovarian cancer are identified every year worldwide and the majority of these woman will die from their disease. When detected early, surgical cure rates exceed 90%, but currently most cases are detected at an advanced stage when the cancer has already disseminated. As such, our most pressing problem in ovarian cancer is a lack of tools to identify early s ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. An Automated Early Motor Development Risk Screener from Observational Video Recordings of Infants and Toddlers

    SBC: BSOLUTIONS, INC.            Topic: NICHD

    Motor development plays a pivotal role in an infant’s overall development and has a cascading effect on social, cognitive, memory, and language ability. These functions can be compromised when motor development is disrupted; motor disruption is associated with generalized developmental delays. Early screening and identification of delays can allow early interventions with the goal of not just im ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Sleeping Beauty Engineered B Cells for Mucopolysaccharidosis

    SBC: IMMUSOFT CORP            Topic: 300

    Project Summary Mucopolysaccharidosis type IMPS Iis an autosomal recessive storage disease caused by the absence ofL iduronidaseIDUAresulting in systemic accumulation of glycosaminoglycanGAGstorage materialshepatosplenomegalyskeletal dysplasiascardiopulmonary obstructionprogressive neurologic impairment and death by ageMPS I is currently treated by enzyme replacement therapy and by allogeneic hema ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Optimization of an innate immune stimulating adjuvant for an HIV DNA vaccine

    SBC: ORLANCE, INC            Topic: NIAID

    Abstract There is a growing consensus that protection against HIV infection will require BOTH antiviral antibody responses as well as polyfunctional CDand CDT cells with potent lytic activityTo stimulate the breadthpotencyand rate of response requiredProfectus Biosciences intends to utilize its platform technologies based on DNA vaccines combined with genetic adjuvantsAs a step in that directiona ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Prosthesis Smart Alignment Tool: ProSAT Phase 2

    SBC: ORTHOCARE INNOVATIONS LLC            Topic: DHA17008

    This Phase 2 SBIR program will result in a commercializable and clinically tested Prosthetic Smart Auto-Alignment Tool (ProSAT), which addresses the need to facilitate rapid, accurate, quantitative, and systematic diagnosis and adjustment of the physical alignment of a prosthesis. ProSAT is a novel approach to alignment challenges by creating a hybrid sensor and smart tool system that can adjust e ...

    SBIR Phase II 2018 Department of DefenseDefense Health Agency
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