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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Extending Shelf Life of Strawberries, Spinach, Kale and Lettuce via Non-Equilibrium Short-Pulsed Plasma Activated Water Fog

    SBC: AA Plasma LLC            Topic: DLA182002

    Current methods for food transportation and storage are insufficient in eliminating contamination threats from food-borne pathogens, resulting in frequent cases of foodborne illness or costly recalls. Perishable products within the DLAs subsistence supply chain are no exception to this problem. AAPlasma LLC proposes a non-equilibrium (cold) plasma-based solution that will continuously disinfect co ...

    SBIR Phase I 2018 Department of DefenseDefense Logistics Agency

    SBC: Apollo Neuroscience, Inc.            Topic: SOCOM182002

    Apollo is a patent-pending AI software platform that integrates with connected hardware to deliver physiologically-reactive vibration, demonstrated in a double-blind randomizedplacebo-controlled clinical trial, to improve resilience, as measured by heart rate variability, and performance under stress by up to 25%.Using physiological measurement and environmental data, Apollo identifies each users ...

    SBIR Phase I 2018 Department of DefenseSpecial Operations Command
  3. Plasma-Enhancement of Absorbers for Improved Removal of PFOS and PFOA from Water

    SBC: AA Plasma LLC            Topic: 17NCER1A

    New regulations and advisory levels for perfluoroalkyl substances have resulted in increased drinking water treatment costs or abandonment of drinking water sources. Treatment technologies are needed that can achieve low parts-per-trillion levels. Presently, there are insufficient treatment technologies that can destructively remove perfluorooctanoic acid (PFOA) and/or perfluorooctane sulfonic aci ...

    SBIR Phase I 2018 Environmental Protection Agency
  4. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Generation of Tissue Engineered Nerve Grafts from GalSafe Porcine Neurons

    SBC: Axonova Medical LLC            Topic: NINDS

    ABSTRACT Peripheral nerve injuryPNIis a common consequence of trauma or surgeryand the extent of functional recovery is often unsatisfactoryMoreovera particular challenge is the repair ofmajorPNIdefined as injuries where a large segment of a nerve is losti eandgtcmor more proximal injuriese gbrachial plexus or upper armthat necessitate extremely long distances for axonal regeneration to distal end ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Linkage-specific ubiquitylation patterns as highly sensitive markers for neurodegenerative disease

    SBC: LIFESENSORS, INC.            Topic: NIA

    While sensitive imaging tools to detectamyloid and tau proteins and other biomarkers for established Alzheimer s diseaseADand other neurodegenerative diseases are availablesimilar tools for detecting presymptomaticetiologic biomarkers of these diseases are notAmong the earliest steps in AD is a failure of the ubiquitin proteasome pathway to respond to misfolded proteins by causing their degradatio ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Mechanism of action of oligomer-displacing Alzheimer investigation drug, CT1812:Receptor interactions and signaling pathways


    Abstract Aoligomers are considered the most toxic structural form of Amyloid betacausing synaptotoxic changes underlying cognitive decline in Alzheimer s diseaseCogRx has developed the world s first highly brain penetrant drug that selectively displaces oligomers from synaptic receptor sites and clears oligomers from the brain into the cerebrospinal fluidCSFThis first in class drugCTallosterically ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Production and quality analysis of clinical drug for a novel CNS protein kinase inhibitor therapeutic candidate

    SBC: NeuroKine Therapeutics, LLC            Topic: NIA

    ABSTRACT Alzheimer s diseaseADand related dementias are increasing rapidly yetremarkablythere are no approved disease modifying drugsVirtually all trials targeting amyloid related pathways have failed over the lastyearsRegrettablyfew alternative targets or pathways have been exploredThereforethere is an urgent need to explore alternative pathways as monotherapies or as constituents of a multi drug ...

    STTR Phase I 2018 Department of Health and Human Services
  9. MyHealthyPregnancy mobile health app: Combining behavioral science and machine learning for risk communication during the peripartum period

    SBC: Naima Health LLC            Topic: NCCDPHP

    Project Summary Abstract BackgroundPreterm birthsthose that occur prior toweeks of gestationare the leading direct cause of neonatal mortality and morbidityMore thaninbirths in the U Sare pretermwith rates that are disproportionately high among African Americans and families living in povertyregardless of raceAddressing the problem of preterm birth requires both accurate identification of the fact ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. A novel PEDF peptide mimetic for diabetic retinopathy

    SBC: Skyran Biologics, Inc.            Topic: NEI

    AbstractThe overall goal of Skyran Biologics is to develop a powerful topical therapeutic to combat diabetic retinopathyDRa leading cause of vision loss and total blindness globallyOur research team was one of the first to show that a novel proteinPigment Epithelium Derived FactorPEDFis expressed in the eye and provides significant protection to the injured retinaAfter identifying amer bioactive r ...

    STTR Phase I 2018 Department of Health and Human Services

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