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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Tomographic Nanoscopy for Pathogen Identification
SBC: SOLID STATE SCIENTIFIC CORPORATION Topic: CBD171003This effort will augment the capabilities of an existing all reflecting, confocal FTIR microscope to allow for digital holographic imaging as wellspectral content determination at video frame rates. The use of a dual beam frequency comb, with a beam path coincident with the pathrequired for the digital holographic imaging, will allow spectral determination of any organism being holographically ima ...
SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Process Development and Manufacture of an Antibody-based Therapy Against Sudan EbolaVirus
SBC: BIOFACTURA, INC. Topic: CBD171005Recently we have observed a massive outbreak of Ebola virus. This family of virus causes a significant bioterrorism threat due to the high levelof mortality, rate of transmissibility and the lack of an approved vaccine or therapy directed against it. The goal of this proposal is to develop,optimize and scale-up a mammalian cell culture-based bioprocess for the rapid manufacture of an antibody-base ...
SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Circulating Diagnostic Markers of Infectious Disease
SBC: PATHOVACS INCORPORATED Topic: CBD18A001The focus of this STTR phase I component is on proof-of-concept studies demonstrating applicability of technical approaches for identificationof circulatory diagnostic markers for infectious disease. Therefore, the primary objective of this project is to determine feasibility of one suchtechnical approach called Proteomics-based Expression Library Screening (PELS), for identification of pathogen-d ...
STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases
SBC: CFD RESEARCH CORPORATION Topic: CBD18A001In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...
STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Marburg Virus Prophylactic Medical Countermeasure
SBC: MAPP BIOPHARMACEUTICAL, INC. Topic: CBD18A002There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...
STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Host-Targeted Antiviral Drugs Providing Rapid, Scalable, Stable, Broad-Spectrum MedicalCountermeasure Against Marburg Virus
SBC: EVRYS BIO LLC Topic: CBD18A002In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...
STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Virus-Like Particle Based pan-Marburgvirus Vaccine
SBC: LUNA INNOVATIONS INCORPORATED Topic: CBD18A002Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...
STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Marburg Virus Prophylactic Medical Countermeasure
SBC: Flow Pharma, Inc. Topic: CBD18A002Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...
STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense -
Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications
SBC: GENECAPTURE, INC. Topic: CBD15C001GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...
STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense -
MicroLens Hyperspectral Imager for Standoff Chemical Detection
SBC: SURFACE OPTICS CORP. Topic: CBD171002A program to develop a compact, MLA-based, LWIR hyperspectral imager is proposed. The proposed Hyperspectral Chemical Imaging Sensor(HyCIS) builds upon Surface Optics real-time hyperspectral imaging activities, including our 3D full-motion video spectral imaging (FMV-SI)technology and our MIDIS hyperspectral image processor. Simultaneously sampling 16 or more spectral bands from 8 um to 12 um (MWI ...
SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense