Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development and evaluation of an internet based adaptation of the New Beginnings Program for divorced parents

    SBC: Family Transitions- Programs that Work, LLC            Topic: NICHD

    PROJECT ABSTRACT The proposed research builds on a successful Phase I SBIR grant to develop and test a web based version of a parenting after divorce group interventionthe New Beginnings Programwhich has been shown in two randomized trials to reduce youthsproblem behaviors and enhance their developmental competencies in theyear period after their parents participatedThe proposed web based format w ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. High-throughput nanoMEA-based Proarrhythmia Assay

    SBC: Nanosurface Biomedical, Inc.            Topic: NHLBI

    PROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Interstitial Intensity Modulated Photodynamic Therapy Phase II

    SBC: SIMPHOTEK, INC.            Topic: NCI

    Photodynamic therapyPDTis a cancer treatment that utilizes visible or near infrared light to activate a lightsensitive drugphotosensitizerPSthatin turncreates reactive singlet oxygen species from ground triplet state oxygen that is present in the tumorThe resulting reactive products induce tissue deathIdeally the reactive species will be produced within only the target volumeleading to damage of t ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. TrachAlarm: A novel, low-cost accessory to automatically detect and alert caregivers to tracheostomy tube decannulation

    SBC: Innovations Unlimited LLC            Topic: NINR

    ABSTRACT The objective of the Phasegrant is to designdevelopand demonstrate feasibility of TrachAlarma novellow cost accessory to automatically detect and alert caregivers when a tracheostomy tube has become accidentally removed from the patientTracheostomy provides a criticallife supporting function for overmillion individuals in the United States with overnew procedures performed each yearEach o ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Lab-To-Marketplace: Commercialization of a stretchable microelectrode array

    SBC: BMSEED LLC            Topic: 101

    Project Summary Abstract The proposed work is directed at the commercialization of BMSEEDandapos s Micro Electrode Array Stretching Stimulating und Recording EquipmentMEASSuREtechnologyMEASSuRE bridges the gap between in vitro and in vivo research by simulating the biomechanical and electrical environment of cells in the body in a controlled environment outside of the bodyThe applications for MEAS ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Early Detection of Ovarian Cancer Using Uterine Lavage and Duplex Sequencing

    SBC: Twinstrand Biosciences, Inc.            Topic: 102

    TBD

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Sleeping Beauty Engineered B Cells for Mucopolysaccharidosis

    SBC: Immusoft Corporation            Topic: 300

    Project Summary Mucopolysaccharidosis type IMPS Iis an autosomal recessive storage disease caused by the absence ofL iduronidaseIDUAresulting in systemic accumulation of glycosaminoglycanGAGstorage materialshepatosplenomegalyskeletal dysplasiascardiopulmonary obstructionprogressive neurologic impairment and death by ageMPS I is currently treated by enzyme replacement therapy and by allogeneic hema ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Feature Learning For Improved Multiplex Disease Diagnosis

    SBC: Deurion R&D LLC            Topic: 400

    Abstract This proposal is for CATTSa feature learning technique optimized for use in multiplex mass spectrometryMSfingerprinting assaysMS fingerprints consist of a large number of chemical speciesleading to very high dimensional feature spacesand subsequent high false discovery ratesCATTS aims to reduce the size of this spaceby using knowledge of the underlying biochemistryas well as general purpo ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Chemokine-receptor expression profiling in biological samples from human clinical trials

    SBC: Plumeria Therapeutics, Inc.            Topic: NINDS

    Project Summary AbstractChronic pain is a major healthcare burdenrepresenting economic costs of up to $B per yearmore than cancerdiabetesand heart diseasePain is a highly heterogeneous condition comprising neuropathicnociceptive and inflammatory componentsand patient responses to currently available drugs vary greatlyA very promising approach to target various forms of pain is through antagonism o ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Optimization of an innate immune stimulating adjuvant for an HIV DNA vaccine

    SBC: Orlance, Inc.            Topic: NIAID

    Abstract There is a growing consensus that protection against HIV infection will require BOTH antiviral antibody responses as well as polyfunctional CDand CDT cells with potent lytic activityTo stimulate the breadthpotencyand rate of response requiredProfectus Biosciences intends to utilize its platform technologies based on DNA vaccines combined with genetic adjuvantsAs a step in that directiona ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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