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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: LUCERNA INC            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Memory Instrumentation and Performance Simulation (MIPS)

    SBC: ATC-NY INC            Topic: DTRA172003

    Next-generation high-performance computing (HPC) hardware, such as the Intel Xeon Phi Knights Landing Many-Integrated-Core processor, provide new deep memory architectures that offer the promise of increased performance. The challenge in taking full advantage of this architecture is selecting which data structures will be placed in the high-bandwidth memory. Optimizing data structure placement in ...

    SBIR Phase I 2018 Department of DefenseDefense Threat Reduction Agency
  3. Topic 374: Topical Delivery of Nanoformulated Bioactive Chemopreventive Agent in Skin Cancer

    SBC: VASCULAR VISION PHARMACEUTICAL CO            Topic: NCI

    We plan to evaluate the chemopreventive management of solar ultraviolet (UV) mediated DNA damage by two different Nanoformulation of epigallicatechin-3-gallate (EGCG). The formulations to be assessed under this study include: a) chitosan based formulation of EGCG (nano-EGCG), and b) EGCG containing chitosan based solid lipid nanoparticles (E-Ch-SLNPs). EGCG is well-tested and popular polyphenol in ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: KITWARE INC            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. STEM and Health: Science Kits Integrating STEM Concepts with Human Health

    SBC: Science Take-Out, LLC            Topic: 500

    ABSTRACT Solving human health problems often involves technologies developed through the collaborative work of scientistsengineersand mathematiciansDespite the fact that STEMsciencetechnologyengineeringand mathematicscollaboration is a crucial aspect of medical research and healthcare careersmany students are still learning scienceengineeringand math as isolated disciplinesIn additionmany teachers ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Tailored Approach to Promoting Engagement in Public Health

    SBC: Transcendent International, LLC            Topic: NINR

    PROJECT SUMMARY Successfully reaching and enrolling fully representative target populations in public health interventions is a highly desiredbut notoriously difficultprospectespecially when an initiative is focused on socially charged issues or health conditions that affect vulnerable subgroupsFor exampleHIV AIDS has disproportionately high morbidity among a number of minority marginalized popula ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A Universal Flu Vaccine Based On Conformationally Locked Soluble Headless HA

    SBC: Calder Biosciences Inc.            Topic: NIA

    An Influenza pandemic remains an acute threat to world health; and stockpiling a universally protective Influenza vaccine provides a strong defense against this potential catastrophe. The hemagglutinin (HA) protein is the primary target of humoral Ab responses to Influenza; the majority of broadly protective mAbs (bnAbs) against influenza isolated from humans recognize conserved and conformation-s ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. RECAL:A New Tool for Disease Detection and Biomolecular Imaging

    SBC: Photon Biosciences LLC            Topic: 400

    Project SummaryAbstract We envision developing a new ultrasensitive detection platform that combines a recombinant protein with a unique imaging media that results in a luminescent protein that is non bleaching and non blinkingThe excitation and emission wavelengths of this protein can be tuned with the choice of imaging media and span much of the visible and near infrared regions of the electroma ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Activating latent growth factors for cartilage regeneration

    SBC: INNOVATIVE ELEMENTS, LLC            Topic: NIA

    Project summary Articular cartilage lesions are prevalent disorders affecting millions of AmericansDeprived of spontaneous healing capacitycartilage lesions may further deteriorate and lead to the onset of osteoarthritisOAOA represents a leading cause of chronic disabilities in the U Sand ultimately warrants total joint arthroplastyA common aspiration in orthopedic medicine is to regenerate the da ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A novel nutraceutical drug for tendinopathy treatment

    SBC: NEW YORK R & D CENTER FOR TRANSLATIONAL MEDICINE & THERAPEUTICS INC            Topic: NCCIH

    PROJECT SUMMARYThis study aims to prove the concept and feasibility that oral administration of Ea product formulated from a combination of generally regarded as safe compoundsGRASexerts therapeutic efficacy on tendinopathyTendinopathy is a common chronic tendon disorder that affects young athletes andof individuals overyears oldIt is characterized by painswellingloss of functionand impaired perfo ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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