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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Generation of Tissue Engineered Nerve Grafts from GalSafe Porcine Neurons
SBC: Axonova Medical LLC Topic: NINDSABSTRACT Peripheral nerve injuryPNIis a common consequence of trauma or surgeryand the extent of functional recovery is often unsatisfactoryMoreovera particular challenge is the repair ofmajorPNIdefined as injuries where a large segment of a nerve is losti eandgtcmor more proximal injuriese gbrachial plexus or upper armthat necessitate extremely long distances for axonal regeneration to distal end ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Linkage-specific ubiquitylation patterns as highly sensitive markers for neurodegenerative disease
SBC: LIFESENSORS, INC. Topic: NIAWhile sensitive imaging tools to detectamyloid and tau proteins and other biomarkers for established Alzheimer s diseaseADand other neurodegenerative diseases are availablesimilar tools for detecting presymptomaticetiologic biomarkers of these diseases are notAmong the earliest steps in AD is a failure of the ubiquitin proteasome pathway to respond to misfolded proteins by causing their degradatio ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Mechanism of action of oligomer-displacing Alzheimer investigation drug, CT1812:Receptor interactions and signaling pathways
SBC: COGNITION THERAPEUTICS, INC. Topic: NIAAbstract Aoligomers are considered the most toxic structural form of Amyloid betacausing synaptotoxic changes underlying cognitive decline in Alzheimer s diseaseCogRx has developed the world s first highly brain penetrant drug that selectively displaces oligomers from synaptic receptor sites and clears oligomers from the brain into the cerebrospinal fluidCSFThis first in class drugCTallosterically ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
High-throughput nanoMEA-based Proarrhythmia Assay
SBC: CURI BIO, INC. Topic: NHLBIPROJECT SUMMARY Failure of new drugs at late stages of development is an extremely costly event commonly associated with the detection of unexpected arrhythmogenic properties in novel drugs Undetected arrhythmia inducing effects are also a common reason for drug withdrawal from the market As a result the FDA now mandates that all new drugs be tested for potential arrhythmogenic properties which ha ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a JBS HI-LO Urine DNA Kit
SBC: JBS SCIENCE INC Topic: 172Development of a JBS Hi Lo urine DNA kit There is a critical need for sensitive and cost effective technologies that can obtain high quality and comprehensive genomic data from easy to collect and handle human specimensCurrentlyfresh or frozen whole blood is the most commonly used source to obtain high quality and comprehensive genomic dataHoweverthe use of whole blood requires stringent collectio ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia
SBC: Cascade Biotechnology Topic: NHLBIAbstract We propose to develop analogs of human complement Cthat have the ability to form a stable CconvertaseIn additionthese proteins will be designed to decrease the affinity of the proteins for factor H bindingAll proteins will be expressed in the Baculovirus insect protein expression systemand tested for their ability to form a stable Cconvertase enzyme that is able to deplete complement in h ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Transforming STEM Education in K-12 using the Biological Interactive Outcomes Modular Environment (BIOME)
SBC: IQ Smart Interactive LLC Topic: 500PROJECT SUMMARYThe United States is falling behind in Science and Math according to results from the Programme for International Student AssessmentPISAranking the US asth in Science andth in Mathematics out ofcountriesThese unfortunate statistics could be attributed to teacher hesitations in teaching math and scienceinability to excite student interest in STEM subjectsor an unclear real world appl ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Interstitial Intensity Modulated Photodynamic Therapy Phase II
SBC: SIMPHOTEK, INC. Topic: 102Photodynamic therapy (PDT) is a cancer treatment that utilizes visible or near-infrared light to activate a light- sensitive drug (photosensitizer, PS) that, in turn, creates reactive singlet oxygen species from ground triplet state oxygen that is present in the tumor. The resulting reactive products induce tissue death. Ideally the reactive species will be produced within only the target volume, ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A generalized Diabetes Networking Tool (DNT) to enhance social support for patient self management
SBC: STARSHIP HEALTH TECHNOLOGIES LLC Topic: 200Abstract We propose to develop a social computing technology called the Diabetes Networking ToolDNTthat enhances Type II Diabetes and pre diabetes patientsability to self manage and avoid disease complications by bolstering familyhouseholdand community based support mechanismsType II Diabetes Mellitus is a life long condition that is a serious and growing public health problemand that requires con ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Heart-health Networking App to help persons returning from incarceration manage cardiovascular disease
SBC: STARSHIP HEALTH TECHNOLOGIES LLC Topic: NHLBIWe propose to develop a mobile health smartphone applicationappcalled the HEart health Networking AidHENAto help persons returning from incarceration into open societyHENA will help them manage cardiovascular diseaseCVDduring their re integration periodand in the broader context of other health and non health related challenges they faceMore thenpersons are released each year from state and federa ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health