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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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2-HOBA for Treatment of Pulmonary Hypertension
SBC: MTI Biotech Incorporated Topic: NHLBIPROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
The re-activatable Yb-169 radiation source: a therapeutic medical device to reduce the risk of brachytherapy and increase adoption
SBC: PXALPHA, L.L.C. Topic: NCIPROJECT SUMMARY/ABSTRACT: There is currently a technological gap in high-dose-rate brachytherapy (HDR-BT) that has stunted the efficacy of single-fraction HDR-BT monotherapy for prostate cancer patients and is preventing a shift away from invasive interstitial brachytherapy to an intracavitary-only approach for cervical cancer patients. The gap is due to the radiation dose conformity limitations o ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Efficacy of an Electrophile Scavenger in the Prevention of Gastrointestinal Inflammatory Carcinogenesis
SBC: MTI Biotech Incorporated Topic: 102SUMMARY: Many cancers are recognized to have an inflammatory etiology. Gastric cancer, the third leading cause of cancer deaths worldwide, is the prototype- it is caused by infection with the bacterial pathogen Helicobacter pylori in 90% of cases. For colorectal cancer (CRC), the second leading cause of cancer deaths, inflammatory bowel disease (IBD) is a frequent precursor lesion. This STTR Phase ...
STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health -
2-HOBA for Treatment of Pulmonary Hypertension
SBC: MTI Biotech Incorporated Topic: NHLBIPROJECT SUMMARY Although the ubiquity of metabolic problems in pulmonary hypertension (PH) has been known for more than a decade, a wealth of new details on the nature of this problem presents the opportunity for intervention. A combination of experimental work in cells and animals and early trials in humans, suggests that these metabolic problems are part of the causation for PH, and that inactiv ...
STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health -
Evaluation of In Vivo Efficacy of a Novel Microbial Therapy to Treat Cognitive Deficits in Alzheimers disease
SBC: PROBIOME THERAPEUTICS, INC. Topic: NIAPROJECT SUMMARY/ABSTRACT Alzheimer’s disease (AD) is a leading cause of dementia, yet no effective therapeutic intervention is available for those in prodromal and early stages of AD. Restoration of functional and cognitive resilience in early disease stages is especially beneficial in many aspects as it could substantially extend the period of quality of life and delay the clinical onset of AD. ...
STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health -
Generalizing and Standardizing fMRI Tools for Differentiating Mental Illnesses and Predicting Medication-Class Response in Patients
SBC: ADVANCED BIOMEDICAL INFORMATICS GROUP, L.L.C. Topic: 102Project Summary/AbstractMood disorders, like many psychiatric conditions, have their onset in emerging adulthood and often last a lifetime. Mental illnesses have an excessively large loading of Disability Adjusted Life Years, making early intervention crucial for both individuals and society. Differentiating bipolar disorder (BD) from major depressive disorder (MDD) based on the Diagnostic and Sta ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
An Automated Patient Chart Error Detection System for Radiation Therapy
SBC: Infondrian LLC Topic: 101Project Summary/Abstract Every year, approximately 1,200 severe mistreatments happen in radiation therapy. Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $313,000 per claim settled or litigated. The current method for detecting treatment errors is by a weekly patient chart check, where each treatment record is manually reviewed on a weekly basis. Thi ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
An aptasensor to distinguish Dengue virus from Zika virus
SBC: Aptalogic, Inc. Topic: NIAIDThe diseases caused by dengue virusesDENVmosquito borne members of the family Flaviviridaehave emerged as the most important arthropod borne viral diseases of humansThe frequencygeographical distributionand severity of DENV epidemics have increased dramatically over the past decadeDENV is spread by mosquito species that also harbor Zika virusZIKVand yellow fever virusAlthough these viruses are end ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Device for Multi-Frequency Oscillatory Ventilation in Adult Patients with the Acute Respiratory Distress Syndrome
SBC: OSCILLAVENT INC Topic: NHLBIProject SummaryAbstractRespiratory failure from the acute respiratory distress syndromeARDSaccounts formillion ICU days annually in the U Splacing a significant burden on public health resourcesLung protective ventilation relies on positive end expiratory pressurePEEPto limit end expiratory derecruitmentand low tidal volumes to reduce inspiratory overdistentionWhile such ventilatory strategies hav ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Improved detection of bladder cancer recurrence using a biophysical biomarker
SBC: SynderBio Inc. Topic: 102Bladder cancer is the fifth most commonly diagnosed cancer in the United StatesThree quarters of the nearlymen and women diagnosed with bladder cancer just this year will have a less aggressive form of the disease whichafter treatmentwill require frequent visits to the urologist for invasivepainful cystoscopy procedures for the remainder of their lifetimes to determine if the cancer has returnedAn ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health