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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Enhancing Clergy Suicide Prevention and Referral

    SBC: ACADEMIC EDGE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Suicide is the 2nd leading cause of death in persons aged 25-34, the 3rd leading cause of death among people in the age groups 10-14 and 15-24, and the 8th leading cause of male deaths. Faith leaders and clergy have been identified in national strategic public health documents as important front-line gatekeepers for suicide prevention. Preliminary research by t ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Method to Guarantee Quality of Radiotherapy Planning

    SBC: ADVANCED PROCESS COMBINATORICS, INC.            Topic: N/A

    This project will produce a method for constructing treatment plans with a guarantee on the quality of the solution. The plans produced by current techniques can fall short of the optimum or needlessly fail to satisfy constraints. As a result, the search for an improved solution is open-ended, exhausting hospital resources and manpower, and providing no assurance to patient or physician that a b ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. Method to Guarantee the Quality of Radiotherapy Planning

    SBC: ADVANCED PROCESS COMBINATORICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This project will develop a package of planning products for radiation treatment that will introduce a measure of quality assurance now lacking, provide clinicians the opportunity to raise tumor dose, and expose the tradeoffs among the treatment constraints and objectives. The new approach based on mixed integer programming (MIP) will ensure that the dose distr ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Chelate Based Scaffolds (Chelabody) In Tumor Targeting

    SBC: COMCHEM TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The current paradigm in therapeutic nuclear medicine is to optimize receptor binding molecules and then add on a moiety capable of carrying a radioisotope. This "afterthought" modification process results in suboptimum performance for such agents when dealing with molecules smaller than monoclo ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  5. Folate Targeted Delivery of a CDKI

    SBC: ENDOCYTE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Ovarian cancer is the second most common gynecological malignancy and is the fourth leading cause of cancer mortality in women. Ovarian cancer is the second most common gynecological malignancy and is the fourth leading cause of cancer mortality in women. Nationwide 23,400 new cases will be diagnosed in 2002 and 13,900 women will die of ovarian cancer. Only 25% ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  6. DIRECT SAMPLE ANALYSIS WITH AN ATMOSPHERIC PRESSURE GLOW DISCHARGE

    SBC: Prosolia, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this Phase I STTR project is the commercialization of a new ionization source for ambient mass spectrometry based on the flowing afterglow of an atmospheric pressure glow discharge (APGD). This technology promises to have significant impact in pharmaceutical, clinical and biomedical research and its potential for enabling in vivo mass s ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Redox protein APE1/Ref-1 as a target for age-related macular degeneration (AMD)

    SBC: APEX Therapeuitcs, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the leading cause of severe vision loss in people over age 60 and an estimated 8 million older-age Americans are at high risk to develop advanced AMD. Among two types of AMD, neovascular (wet) and non-neovascular (dry), neovascular AMD causes 90% of the vision loss. The key pathogenesis of the neovascular AMD is neovasc ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Kidney Multiphoton Analysis of Therapeutic Agents

    SBC: INPHOTON, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The integrated scientific team of INphoton, LLC will develop standard operating procedures for intravital multiphoton microscopy assays quantifying fluorescent drug delivery, cellular uptake, intracellular distribution, metabolism, and physiologic/therapeutic effects within the kidney of live rats. Refinement of some existing assays will be necessary for commer ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel High-Intensity Area X-ray Source

    SBC: Nesch, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diffraction enhanced imaging (DE I) is a novel approach to X-ray imaging, which can revolutionize X-ray medical imaging, because of its greater contrast at lower X-ray doses than conventional radiography. DEI relies on measuring tiny angular deflections of a collimated X -ray beam as it passes through the object (patient) in acquiring the images. The capabil ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Large-area X-ray diffraction crystal optics

    SBC: Nesch, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diffraction enhanced imaging (DEI) is a novel approach to X-ray imaging which can revolutionize X -ray medical imaging, because of its greater contrast at lower X-ray doses than conventional radiography. DEI relies on X-ray optics of perfect crystals to acquire these images by measuring tiny angular deflections of a collimated X-ray beam as it pass es throug ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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