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MERCURY IS A HIGHLY TOXIC MATERIAL THAT OCCURS IN BOTH ORGANIC AND INORGANIC FORMS. BECAUSE OF ITS WIDESPREAD INDUSTRIAL USE THE WHOLE POPULATION IS EXPOSED TO MERCURY COMPOUNDS EVERYDAY. THERE IS A NEED FOR A FAST, EASY TO USE, INEXPENSIVE, SENSITIVE METHOD FOR THE DETECTION OF MERCURY TO REDUCE THE RISK OF CHRONIC EXPOSURE. OUR OBJECTIVE IS TO DEVELOP A NEW TECHNIQUE FOR THE SELECTIVE DETECTION ...

AN ASSAY SYSTEM FOR MONITORING FUNCTIONAL FIBRINOGEN IN PATIENTS UNDERGOING THROMBOLYTIC THERAPY WILL BE DEVELOPED. THIS SYSTEM WILL BE BASED ON A NOVEL DRY REAGENT ASSAY TECHNOLOGY THAT HAS RECENTLY BEEN APPLIED SUCCESSFULLY TO PTAND ACTIVATED PTT TESTS. INTRODUCTION OF A RAPID, CONVENIENT, FIBRINOGEN ASSAY SYSTEM ON A DECENTRALIZED BASISCOULD PROVIDE ACCURATE RESULTS SOONER THAN EXISTING LABORAT ...

BORON NEUTRON CAPTURE THERAPY (BNCT) HAS A CLEAR THEORETICALADVANTAGE OVER OTHER TECHNIQUES AS A METHOD OF DELIVERING CELL-KILLING RADIATION TO CANCEROUS TUMORS. COMPOUNDS CONTAINING THE ELEMENT BORON, SUCH AS BORONOPHENYLALANINE (BPA), CAN ALSO SELECTIVELY LOCALIZE IN SKIN CANCERS SUCH ASMALIGNANT MELANOMA. UPON IRRADIATION BY A THERMAL OR EPITHERMAL NEUTRON BEAM, THE COMPOUND PRODUCES LOCALIZED ...

THE INABILITY TO DETECT TOXINS WITH ADEQUATE SENSITIVITY IS ONE OF THE PRINCIPAL REASONS THAT THEY ARE POTENTIALLY THREATENING, EITHER DUE TO "NATURAL" EXPOSURE OR DELIBERATE AND HOSTILE USE OF THESE AGENTS BY AN ADVERSARY. THIS PROPOSAL OUTLINES A WAY THAT THE DETECTION OF THESE TOXINS CAN BE MADE MUCH MORE SENSITIVE WITHOUT USE OF EXPENSIVE EQUIPMENT OR HIGHLY TRAINED PERSONNEL FOR THE FINAL PRO ...

MOLTEN SALT LITHIUM BATTERIES OFFER THE PROSPECT OF VERY HIGH PULSE POWER DENSITIES COUPLED WITH HIGH SPECIFIC ENERGY DENSITIES. FOR PULSE POWER APPLICATION, U.S. ARMY REQUIRES PROJECTED CURRENT DENSITIES OF HUNDREDS OF AMPERES PER SQ.CM. IN THE MILLISECOND RANGE AND TENS OF AMPERES PER SQ.CM. IN THE FRACTIONS OF SECOND. CATHODES FOR SUCH MOLTEN-SALT LITHIUM BATTERIES MUST HAVE HIGH THEORETICAL EN ...

THE PHASE I PROGRAM WILL DEVELOP AN INNOVATIVE TEACHING MODEL FOR TRAINING SURGEONS IN MICROVASCULAR ANASTOMOSIS TECHNIQUES. PRACTITIONERS OF MICROSURGERY MUST BE ABLE TO JOIN TOGETHER THESE VESSELS OF APPROXIMATELY 1 MM IN DIAMETER. GREAT SKILL IS NECESSARY TO REPAIR THESE SMALL VESSELS DURING SURGERIES THAT INCLUDE REPAIR OF HUMAN DIGITS, TRANSPLANTATION, AND REPLANTATION. ONCE ACQUIRED, MICROSU ...

]THE PURPOSE OF THIS PHASE I EFFORT WILL BE TO DEVELOP AND TEST IN PROTOTYPE AN INNOVATIVE FACE MASK TO FIT THE HYBRID III MANIKIN HEADS. THE MASK WILL BE DESIGNED SPECIFICALLY TO BE SUITABLE FOR MEASURING FACIAL LACERATION POTENTIAL DURING VARIOUS TRAUMA RESEARCH EFFORTS. THIS MASK WILL BE CONSTRUCTED OF COMPOSITES THAT MIMIC MANY CHARACTERISTICS OFLIVING HUMAN SKIN AND WILL CAUSE MINIMAL DYNAMIC ...

THIS SBIR PHASE I PROPOSAL SPECIFICALLY ADDRESSED 'EARLY STAGE' DEVELOPMENT ISSUES INVOLVED IN APPLYING FIELD EMISSION (FEA) TECHNOLOGY TO BUILD A MONOCHROME, FLAT SCREEN, PAGE SIZE, HIGH CONTRAST, HIGH RESOLUTION DISPLAY. A 90 MM DIAGONAL 700 X 7000 LINE BLACK AND WHITE HE LMET DISPLAY IS THE TARGETED PHASE II PRODUCT. COLOR DISPLAYS AND 138 MM DIAGONAL DISPLAYS ARE TARGETED TO FOLLOW THE INITIAL ...

A PHASE I PROGRAM IS PROPOSED TO INVESTIGATE THE POTENTIAL FOR DEVELOPMENT OF NEW CUTTING/LUBRICATING FLUID SLURRIES THAT WOULD HAVE SIGNIFICANTLY HIGHER THERMAL CAPACITIES THANTHOSE CURRENTLY AVAILABLE AND WOULD HAVE POTENTIAL APPLICATION TO HIGH-SPEED MACHINING. SIGNIFICANT RESULTS HAVE BEEN ACHIEVED ON A NUMBER OF OTHER SBIR PROJECTS AT TRDC (FOR NASA AND DOD) THAT HAVE UTILIZED PRESSURIZED, CL ...

THE OBJECT OF THIS PROPOSED RESEARCH IS TO PRODUCE MORE RELIABLE ESTIMATES OF EXTREME WINDS IN THE UNITED STATES BY SEPARATELY ANALYZING WINDS DUE TO THUNDERSTORMS AND LARGE SCALE EXTRATROPICAL STORMS. THE PRESENT STATE OF THE ART METHODS FOR ESTIMATING DESIGN WIND SPEEDS IN NON-HURRICANE REGIONS OF THE UNITED STATES DO NOT DISTINGUISH BETWEEN WINDS ORIGINATING FROM THE LARGE SCALE EXTRATROPICAL P ...