You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 207728 results
  1. ZYNPEPTIDES AS MODULATORS OF RESPONSES TO BIOMATERIALS

    SBC: Zynaxis, Inc.            Topic: N/A

    INTRAVASCULAR STENTS ARE SPRING-LIKE DEVICES WHICH ARE PLACED IN ATHEROSCLEROTIC HUMAN CORONARY AND ILIAC ARTERIES TO KEEP THEM FROM COLLAPSING AFTER BALLOON ANGIOPLASTY. A NECESSARY ADJUNCT TO STENT IMPLANTATION IS SYSTEMIC ANTIPLATELET AND ANTICOAGULANT THERAPY TO PREVENT ACUTE THROMBOSIS WITH THE ATTENDANT RISK OF UNWANTED BLEEDING. ZYNAXIS CELL LINKERS, WHICH BIND TIGHTLY TO PERIPHERAL BLOOD C ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. Zyn-Linkertm/Heparin Conjugate to Prevent Restenosis

    SBC: Zynaxis, Inc.            Topic: N/A

    RISK ASSESSMENT FOR CHRONIC HEART DISEASE (CHD) USES INDIRECT ESTIMATES OF LDL CHOLESTEROL FROM TOTAL CHOLESTEROL, HDL AND VLDL ESTIMATES. NO CLINICAL ASSAY EXISTS TO QUANTITATE LDL DIRECTLY FROM SERUM. WE WILL USE A MODEL LDL DETERMINATION ASSAY USING PKH26-ZYN-LINKER LABELLED LDL PARTICLES (LDLS) TO QUANTIFY LDLS DIRECTLY RATHER THAN USING TRADITIONAL PRECIPITATION TYPE ASSAYS AND CALCULATED LDL ...

    SBIR Phase II 1995 Department of Health and Human Services
  3. Zyn-Linkertm/Heparin Conjugate to Prevent Restenosis

    SBC: Zynaxis, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Health and Human Services
  4. ZW800-1: The 1st Zwitterionic NIR Fluorophore for Cancer Imaging and Ureter Mapping

    SBC: Curadel, LLC            Topic: 102

    Image-guided surgery using invisible near-infrared (NIR) fluorescent light is here to stay. Multiple commercial imaging systems from Stryker, Olympus, Medtronic, and Intuitive Surgical are now available for human surgery. However, only innovative NIR fluorophores will solve major clinical problems.Curadel has invented a novel family of NIR fluorophores termed “zwitterionic,” or more precisely, ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. ZW800-1: The 1st Zwitterionic NIR Fluorophore for Cancer Imaging & Ureter Mapping

    SBC: Curadel, LLC            Topic: 102

    PROJECT SUMMARY ABSTRACTImage guided surgery using invisible near infraredNIRlight is in the midst of a renaissanceMultiple commercial imaging systemsincluding Curadel s state of the art FLAREsystemare available for preclinicalveterinaryand human surgeryHoweverthe ultimate success of the field will depend on innovative NIR fluorophores that solve important clinical problemsCuradel has invented a n ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Zwitterionic oxime (RS194B) to reverse advanced symptoms and lethality of organophosphate pesticide exposure

    SBC: Plant Vax, Inc.            Topic: 105

    ABSTRACTInhibition of AChE in the neuromuscular junctionperipheral autonomic and central neuron synapsesand on circulating red blood cells is associated with the toxicity for all organophosphate insecticidesTreatment typically involves the muscarinic antagonistatropinein combination with a pyridinium aldoximeeg pralidoximePAMand obidoximecapable of reactivating the OPinhibited AChEwith without an ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Zwitterionic Graft Coatings for Enhanced Orthopedics

    SBC: INNOVATIVE SURFACE TECHNOLOGIES INC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Project Summary This Phase I SBIR project is designed to develop new zwitterionic graft methodology for orthopedic surfaces with enhanced durability. As Americans live longer and more active lives, total joint replacement is becoming more common. Current orthopedic joints have average lifespans of approximately 20 years. By that point wear on the joint causes p ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Zwitterionic Clicking for Enhanced Orthopedics

    SBC: INNOVATIVE SURFACE TECHNOLOGIES INC            Topic: NIAMS

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project is designed to develop new zwitterionic click methodology for orthopedic surfaces with enhanced durability. As Americans live longer and more actives lives, totaljoint replacement is becoming more common. Current orthopedic joints have average life spans of approximately 20 years. By that point wear on th ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Zwitterion-Enzymatic Bioresistant Coating

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: N112166

    Marine biofouling is a significant problem on ship hulls, increasing fuel consumption and decreasing speed/efficiency. Traditional coatings prevent fouling through controlled release of biocidal compounds (e.g. metals, copper or zinc, or organics, tributyltin). The continuous leaching of these biocides has raised environmental impact concerns. A variety of non-biocidal technologies have been attem ...

    SBIR Phase II 2013 Department of DefenseNavy
  10. Z-Wave Directed Energy for Neutralizing IEDs

    SBC: SCIENTIFIC APPLICATIONS & RESEARCH ASSOCIATES, INC.            Topic: A10045

    We have proposed the development of a novel, low frequency, directed energy concept for neutralizing IEDs at a safe distance in front of moving vehicles. The concept is based on launching an"Energetic RF Zenneck-mode Surface Waves"(Z-waves), which unlike conventional RF free field propagation, its intensity falls off at a 1/r rate, and is capable of penetrating ground and shielded enclosures. The ...

    SBIR Phase I 2011 Department of DefenseArmy
US Flag An Official Website of the United States Government