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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Clear Cues: Supportive Wayfinding for Care Communities

    SBC: Linda-&-Cameron, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): The purpose of this project is to develop and test Clear Cues (CC), a signage system for care communities that supports way finding in people with dementia. Way finding is a process through which people use informationin the environment to help them get to their desired destination. It's both the user experience of choosing a path and the design elements t ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Alzheimer's Disease Drug Treatment

    SBC: P2D, INC            Topic: NIA

    DESCRIPTION (provided by applicant): P2D Bioscience is developing the selective, non-addicting dopamine transport (DAT) inhibitor, PD2XXX, for the symptomatic treatment of Alzheimer's disease (AD). The core symptom of AD is short-term memory impairment. (DSM-IV) In preliminary studies, PD2XXX improved short term memory by over 110% in a well-accepted triple transgenic mouse model of AD (3xTg ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A novel antisense therapeutic for treatment of Aspergillus fumigatus infections

    SBC: GUILD ASSOCIATES INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Guild proposes to develop an antisense oligomer-based antifungal effective against the human pathogen Aspergillus fumigatus. With a 40%-60% mortality rate, invasive aspergillosis (IA) due to A. fumigatus now surpasses invasive candidiasis as the most frequent fungal cause of death, especially amongst immunocompromised patients. Successful therapy for IA with cu ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Targeting the Core Binding Factor tumor suppressor in MLL-fusion AML

    SBC: P2D, INC            Topic: NCI

    DESCRIPTION (provided by applicant): RUNX1 is considered a beneficial tumor suppressor in myeloid neoplasms. Inhibition of RUNX1 function has been implicated as an important mechanistic event in the development of core-binding factor-(CBF)-leukemia and MLL-fusion leukemia. Inactivating RUNX1 mutations are frequently found in patients with acute myeloid leukemia (AML). However, RUNX1 mutation is us ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Fecal DNA Testing for Colorectal cancer Screening

    SBC: GLC Biotechnology, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): This is the Phase I application of a SBIR project that will be devoted to develop a new fecal DNA test for CRC screening, which will utilize a new tri-marker panel discovered in our preliminary study. CRC is the seconddeadliest cancer in USA. The good news is that early detection along with resection is associated with a five-year survival rate of nearly 100%. ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Large-Area Plasma Panel Detectors for Particle Beam Radiation Therapy

    SBC: Integrated Sensors, LLC            Topic: NCI

    Abstract A joint DOE-NCI workshop on ion beam therapy (January 2013, Bethesda, MD) has identified an ambitious set of technological developments needed to support a world-class treatment program for ion beam therapy. One important requirement is the ability to provide detectors that afford single-particle registration at high data rates with high degree of uniformity and minimal interference with ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Affinity reagents for the detection of modified RNAs and Transcriptome-wide mapping of RNA modifications

    SBC: GUILD ASSOCIATES INC            Topic: NIDA

    DESCRIPTION (provided by applicant): Biological RNAs undergo extensive post-transcriptional modifications. These modifications are important in promoting the accuracy and efficiency of gene expression in biological systems. To decipher the functions of RNA modifications, robust analytical tools and methods that enable scientists to monitor, manipulate, and transcriptome-wide mapping RNA modificat ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. An Ultra-Stable Insulin Analog with Intrinsic Basal-Bolus Action

    SBC: THERMALIN DIABETES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Pre-mixed formulations of soluble prandial insulin analogs and NPH micro-crystalline suspensions provide a simplified and cost-effective basal-bolus regimen for patients with Type 2 diabetes mellitus (T2DM) not effectively controlled by basal insulin therapy alone. Such twice-daily products (in vials or pre-filled in pens) account for gt 2B in sales in the dev ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. ANTIMICROBIAL COPPER ALLOY COATINGS FOR CONTACT ENVIRONMENTS

    SBC: MesoCoat            Topic: NIBIB

    DESCRIPTION: This Small Business Innovation Research Phase I project shows great intellectual merit. The antimicrobial properties of copper-based alloys continue to be a topic of research interest, and there are no current publications detailing the mechanical properties, corrosion resistance, and anti-microbial characteristics of copper-based alloy bi-layers. Pending a successful Phase I research ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Computational platform for Green Chemistry

    SBC: LEADSCOPE, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): The field of green chemistry was established in order to reduce or even eliminate any negative impact from the introduction of new chemical products such as new pesticides, cosmetics, or drugs to human health or the environment. Unfortunately, current approaches for testing chemicals are expensive, time-consuming and require the use and sacrifice of hundreds of ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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