Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Automated Test of Word Recognition- Phase II

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Over 5 million word recognition tests are administered annually by audiologists in the United States with an associated cost of more than $100 million. These tests are currently performed manually by highly trained audiologists. This application describes the Phase II development of automated clinical speech recognition tests using clinical test recordings and ...

    STTR Phase II 2005 Department of Health and Human Services
  2. Audiometric Earphone- Phase 1

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones emply a supra-aural design that has several undesirable characteristics, including 1) an "occlusion effect", an artificial increase in sensitivity to bon ...

    STTR Phase I 2005 Department of Health and Human Services
  3. Optimal Hydrophobicity of Lipoid Gene Delivery Agents

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cationic lipid-like compounds are commonly used in vitro and in vivo to deliver DNA to cells for the purposes of expressing exogenous genes. A number of clinical trials have indicated the promise of these agents for gene therapy, however lipid-based delivery remains less effective than the alternative viral vectors. Nevertheless, vast improvements have been mad ...

    STTR Phase I 2005 Department of Health and Human Services
  4. MRI Quantification of Postinfarct Myocardial Viability

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop a novel method for MRI quantification of postinfarct myocardial viability. Ultimately, the commercial embodiment of this method will be a software package that will convert a set of 2D cardiac MRI images to a 3D Myocardial Viability Map (MV) with a voxel-by-voxel resolution. In human clinical use, the package woul ...

    STTR Phase I 2005 Department of Health and Human Services
  5. New anti-complement therapy to reduce reperfusion injury

    SBC: ENDOPROTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this proposal is to provide proof-of-concept that a novel therapy that prevents complement activation could be effective in reducing ischemia reperfusion injury (IRI) in transplanted organs. Complement activation after IRI in transplanted organs is a well-known phenomenon that may be responsible for delayed graft function and the hastening of ...

    STTR Phase I 2005 Department of Health and Human Services
  6. Utility of a Novel Anthracycline Analog in Psoriasis

    SBC: GEM Pharmaceuticals            Topic: N/A

    DESCRIPTION (provided by applicant): Psoriasis is a common immune-mediated disease that affects approximately 2% of the US and European populations and significantly impacts the quality of life. T cells are recognized as primary mediators of the disease and new generation therapies aimed at eliminating reactive T cells or interfering with the immunologic cascade caused by their activation have bee ...

    STTR Phase I 2005 Department of Health and Human Services
  7. Internet Savvy Caregiver: Dementia Training and Planner

    SBC: HEALTHCARE INTERACTIVE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the Internet-Based Savvy Caregiver (IBSC) program is to develop and bring to market an Internet-based psycho-educational program designed to provide persons caring for relatives who have dementing disorders the knowledge, skills, and outlook they need to undertake and succeed in the caregiving role they have assumed. The IBSC program is comp ...

    STTR Phase I 2005 Department of Health and Human Services
  8. Rapid Bacterial Detection in Platelet Concentrates

    SBC: Medical Innovations International, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A rapid detection system can be readily developed to prevent bacterial contamination in platelet concentrates that are intended for transfusion. Bacteria contamination of platelet concentrates intended for transfusion, represents the most frequent transfusion-associated infectious risk. Bacterial contamination levels as low as 102 to 103 CFU/ml have been ass ...

    STTR Phase I 2005 Department of Health and Human Services
  9. Rapid Detection of Aspirin Resistance in Human Subjects

    SBC: Medical Innovations International, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The number of patients treated with antiplatelet agents increases annually. It is reported that over 20 million people in the U.S. alone take aspirin daily to induce some level of platelets inhibition. Clinical data shows that not all patients receive the full benefits of aspirin, and that a large patient to patient variability exists in aspirin induced platele ...

    STTR Phase I 2005 Department of Health and Human Services
  10. Enhancement of the Baculovirus Expression Vector System

    SBC: PARATECHS CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): The baculovirus expression vector system (BEVS) is one of the most powerful and versatile eukaryotic expression systems. The BEVS is being used to produce antigens for vaccine development, to manufacture human therapeutics, to develop faster acting biological insecticides and as a protein expression system for a multitude of research project. However, a limita ...

    STTR Phase I 2005 Department of Health and Human Services
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