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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. An Unobtrusive, Multi-individual Gait Monitor

    SBC: RESPONSE APPLICATIONS, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): We will develop an instrument to improve the healthcare of the most frail members of the elderly community. This population; elderly or recovering patients living at home or in an extended care facility is too frail toleave this environment and, as such, is subject to significantly reduced physical activity. Although numerous studies have confirmed that contin ...

    SBIR Phase I 2012 Department of Health and Human Services
  2. Safe and effective anti CD154 antibodies for therapeutic intervention

    SBC: IMMURX LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): In both animal proof of concept studies and preliminary clinical trials, there is ample data demonstrating the potential therapeutic benefits o CD154 blockade for treatment of autoimmune diseases and organ transplantation. However, development of ?CD154 as a therapeutic has been impeded by antibody toxicity observed in early clinical trials. With nearly 50 mill ...

    SBIR Phase I 2012 Department of Health and Human Services
  3. Adherence Monitoring for Substance Abuse Clinical Trials

    SBC: CREARE LLC            Topic: NIDA

    DESCRIPTION (provided by applicant): The evaluation and selection of safe and effective pharmacotherapies for drug abuse and addiction is performed through clinical trials that rely on patients taking the studied medication at the specified time and frequency. To ensure accurate efficacy measures, adherence to the prescribed regimen must be known. Creare proposes to develop an adherence monitoring ...

    SBIR Phase I 2012 Department of Health and Human Services
  4. Cyano-Map: Linking cyanobacteria metrics and human health

    SBC: APPLIED GEOSOLUTIONS LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Research at the intersection of limnology and public health is showing that toxins produced from cyanobacteria act as an environmental trigger for Amyotrophic Lateral Sclerosis (ALS) commonly known as Lou Gehrig's Disease. Additional linkages are being made between cyanobacteria and Parkinson's and several acute illnesses and neurological disorders. A ...

    SBIR Phase I 2012 Department of Health and Human Services
  5. Preclinical Development of a Novel Plaque-Regressing Therapy For Atherosclerosis

    SBC: CELDARA MEDICAL, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the leading cause of death in the world. The staggering mortality rate is expected to increase significantly in the next ten years. In the U.S., an estimated 81 million adults will haveone or more types of cardiovascular disease with an estimated total annual direct and indirect economic burden of 400 billion. Atherosclerosis i ...

    SBIR Phase I 2012 Department of Health and Human Services
  6. Research Platform Integrating Patient Reported and Clinical Outcomes Data Sources

    SBC: DYNAMIC CLINICAL SYSTEMS, INC.            Topic: NLM

    DESCRIPTION (provided by applicant): While large, prospective, blinded trials are the gold standard in clinical research, they require significant commitments of resources and time. Further, since these trials seek the answer to rather specific questions,the applicability and scalability of data obtained in these large trials is limited by the way in which it was collected. These trials will like ...

    SBIR Phase I 2012 Department of Health and Human Services
  7. IGF::OT::IGF OTHER FUNCTIONS- NOVEL IMAGING AGENTS TO EXPAND THE CLINICAL TOOLKIT FOR CANCER DIAGNOSIS, STAGING, AND TREATMENT

    SBC: ARkival Technology Corporation            Topic: NCI

    This technology introduces a new non-invasive, biopsy-adjunct with a MNP platform for targeted tumor delivery. It employs closely sized magnetic nanoparticles (CS-MNP's) for determining their concentration and spatial distribution in tumor vasculatures asmeasured by magnetic resonance imaging (MRI). The relationship between CS-MNP size and Vibrating Sample Magnetometer (VSM) measurement foll ...

    SBIR Phase I 2012 Department of Health and Human Services
  8. SBIR PHASE I- AUTOMATED NALOXONE DELIVERY SYSTEM. OTHER FUNCTIONS

    SBC: CREARE LLC            Topic: NIDA

    The objective of the Phase I project is to prove the feasibility of the Automated Naloxone Delivery System (ANDS) by: (1) designing the physiological monitoring and prediction algorithm used to trigger the injection; (2) designing and developing prototypesof the automated naloxone injection system; (3) conducting structured interviews with potential users (opiate injectors and physicians) to deter ...

    SBIR Phase I 2012 Department of Health and Human Services
  9. Xenon MRI assessment of response to cystic fibrosis therapies

    SBC: XEMED LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): New clinical guidelines for the treatment of exacerbations in cystic fibrosis (CF) were recently published by the American Thoracic Society. Examples of these evidence-based recommendations include not performing synergy testing to combat multi-drug-resistant infections, and using only one daily dose of aminoglycoside antibiotics, which was found equally effect ...

    SBIR Phase I 2012 Department of Health and Human Services
  10. Assessment of lung function in neonates and infants

    SBC: XEMED LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Assessment of lung function in neonates and infants Lung disease is the most common chronic disease of childhood, but methods for assessing lung disease such as spirometry cannot be performed by young children. Thus clinicians have only parental reports of patient symptoms upon which to base treatment decisions. Further, clinical trials of treatments for lung d ...

    SBIR Phase I 2012 Department of Health and Human Services
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