Award Data

Project Summary Opioids like morphine and hydrocodone are generally the most effective therapeutics for treatment of moderate to severe pain. However, their use is limited by serious side effects - tolerance, constipation, respiratory depression, physical dependence and high addictive potential. The frequency of clinical pain, coupled with a lack of alternative therapeutic options has led to a nat ...

The goal of this NIH Phase I SBIR proposal is to develop and validate a new method to monitor the symptomatic toxicities and health related quality of life of cancer patients who are undergoing and have undergone radiation therapy during the course of their treatmentThe proposal is built around expertise in mobile application developmentVivonics Incand radiation oncologyDrTJ Fitzgerald of the Univ ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project lies in the replacement of key petroleum-based chemicals used in the paints and coatings industry, representing a $7B industry that is growing at 7% per year. The total addressable market includes 3 similar diols: 1,4-butanediol (1,4-BDO), 1,5-pentanediol (1,5-PDO), and 1,6-hexanediol (1,6-HDO ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to provide software service to correct Earth observation satellite (EOS) data to at-ground reflectance. EOS must look through the Earth?s atmosphere that induces systematic error in measuring the actual reflectance of ground targets through scatter and attenuation of light. Atmospherically-induced ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to develop a novel web application for faster and more accurate estimation of important physical and chemical properties of materials used by engineers and scientists from various academic and industrial disciplines. Oil and gas, mining, nuclear waste management, and environmental consulting compan ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to develop technology using engineered bacteria to improve protein stability in two large markets: therapeutic proteins and industrial enzymes. Proteins used as therapeutics frequently have insufficient half-lives in human blood plasma, so that patients with chronic disease need to receive ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will result from the development of a traveling-wave parametric amplifier (TWPA) prototype suitable to be marketed to the Quantum Information Processing community. Quantum computers require extremely sensitive amplifiers operating near absolute zero to amplify weak signals. There are two criti ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will enable Fortify to provide U.S. manufacturers with a disruptive manufacturing technology to create low-volume tooling parts with order of magnitude reductions in lead times and part price. U.S. manufacturers rely on prototype and low-volume production parts that are currently produced usin ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is that it will reskill those being displaced by the disruption caused by the impending AI and automation that is sweeping every industry. By providing training and fully integrated career services platforms at significantly lower cost than traditional models, Expercoin Republics will make education m ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project arises from bringing new materials to market for making improved rechargeable lithium ion batteries needed by the high-tech economy, medicine, and the military (batteries are the second largest military consumable). In today's world, everything, including medical devices (e.g., wireless implants and s ...