Award Data

ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

DESCRIPTION provided by applicant ParaTechs Corporation aims to provide researchers with advanced technology and methods to simplify procedures for laboratory animal models While actively supporting efforts to `reduce replace and refineandapos animal use ParaTechs provides safe and efficient alternatives for surgical procedures We have already brought to market a nonsurgical embryo transfe ...

DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...

DESCRIPTION provided by applicant Chikungunya virus CHIKV is an alphavirus classified as a category C priority pathogen that causes fever rash and arthralgia in humans In the past decade CHIKV outbreaks have spread beyond the endemic regions of Africa and Asia first to the islands in the Indian Ocean and most recently to the Americas The World Health Organization has reported that as ...

DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

DESCRIPTION provided by applicant The Fontan procedure or total cavopulmonary connection TCPC is a standard palliative surgery for patients with complex single ventricle congenital heart anomalies TCPC connects the inferior and superior vena cava IVC and SVC directly to the right pulmonary artery bypassing the heart The single ventricle is then reserved for pumping oxygenated blood to th ...

Glycosaminoglycan Interacting Small Molecule GISMO As Parkinsonandapos s Therapeutics ABSTRACT Current approved drugs for Parkinsonandapos s Disease PD treat the symptoms of the disease but do not stop disease progression This project is focused on developing a new disease modifying PD therapeutic with a novel mode of action that is expected to block disease progression Recent data indicate ...

alcohol

PROJECT SUMMARY ABSTRACT Brockman Hastings LLC seeks to reduce vision loss for glaucoma sufferers by creating a simple accurate and clinically acceptable system for monitoring intraocular pressure IOP Trends indicate that by approximately million people worldwide will have glaucoma million of whom will become blind Elevated IOP remains the key risk factor and treated symptom for ...