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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Risperidone Subcutaneous Implant

    SBC: Delpor, Inc            Topic: 101

    DESCRIPTION provided by applicant The objective of the proposed study is to develop a subcutaneous implant of risperidone which provides consistent therapeutic blood levels of the drug for months The benefits of such product include improved medication adherence the ability to withdraw the medication if needed due to treatment emergent Adverse Effects AEs fewer relapses and improved eff ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Non-invasive Blood Alcohol Sensor for Emergency Room Applications

    SBC: Epicentre Technologies Corporation            Topic: 150

    DESCRIPTION provided by applicant Project Summary Accurate quantification of alcohol and drugs of abuse intoxication in emergency rooms ERs is an important screening step for a precise diagnosis and hence for prompt treatment Some severe emergencies such as traumatic head injury diabetes and stroke can be misdiagnosed in the absence of screening for alcohol and drug intoxication reliable ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. MRI-Compatible Fiber-Optically Sensorized Biopsy Needles for Oncological Applicat

    SBC: Intelligent Fiber Optic Systems Corporation            Topic: NIBIB

    DESCRIPTION provided by applicant The goal of this research is to develop an innovative prototypical medical device treatment system capable of detecting and visualizing three dimensional shape and tip position of a biopsy needle during Magnetic Resonance Imaging MRI or other image assisted interventional radiological procedures This work will be done in collaboration with interventional rad ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Cell Lysates to Sequencing Reads: A Multiplex Gene Expression Profiling Tool for

    SBC: BioSpyder Technologies, Inc.            Topic: 172

    DESCRIPTION provided by applicant This proposed Phase I SBIR project will transfer RASL Seq a targeted sequencing technology developed in academia to a small business Xpress Inc and demonstrate feasibility for its commercialization as a platform for drug discovery and high throughput screening HTS The technology detects hundreds of RNA targets at once in cell lysates using oligo li ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Safety of Allogeneic Cardiosphere-Derived Cells for Dilated Cardiomyopathy

    SBC: CAPRICOR, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Project Abstract Capricor Inc has an allogeneic cell therapy product CAP presently in clinical development CAP consists of cardiosphere derived cells CDCs grown from a donor unrelated to the recipient using a proprietary process exclusively licensed to Capricor Autologous CDCs have demonstrated their utility as a regenerative agent able to ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Cloud-Based Bioinformatics for Immune Repertoire Analysis

    SBC: Gigagen, Inc.            Topic: NHGRI

    DESCRIPTION provided by applicant The Specific Aim of this Phase II SBIR grant application is to launch ClonoByteandquot a website and cloud based platform for the processing storage analysis comparison and visualization of immune signature data sets generated by deep sequencing of immune repertoires There is a rapidly growing demand for T cell receptor TCR and immunoglobulin Ig repertoire sequenc ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Commercialization of Magneto-Nanosensor Immunoassay Platform for Cancer Diagnosis

    SBC: Magarray, Inc.            Topic: 102

    DESCRIPTION provided by applicant This project seeks to optimize a promising magneto nanosensor technology for use in cancer diagnosis By adapting a common technology from the computer disk drive industry this simple device enables researchers to simultaneously detect multiple proteins or biomarkers at ultra low concentrations in biological fluids The abundance and change over time of seve ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Magnetic Resonance Imaging Subsystem for Cardiac Ischemia Evaluation

    SBC: HeartVista, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Cardiac magnetic resonance imaging MRI has been shown to be one of the best technologies for the evaluation of cardiovascular pathologies The broad application of this promising technology is expected to significantly improve the treatment of patients with heart disease in general and ischemic heart diseases in particular However widespread adoption of th ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Highly Multiplexed Digital Assays

    SBC: PROGNOSYS BIOSCIENCES, INC.            Topic: 400

    DESCRIPTION provided by applicant There is a need for new technologies to enable multiplexed analysis of collections of biomarkers in biological samples We propose to develop a novel assay format for detecting and analyzing many biomarkers simultaneously In order to do this we will develop reagents and methods and validate the approach using a model system If successful our long term goal i ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Development of OCT Imaging Adapter for Interstitial Tissue Imaging

    SBC: WEST FACE MEDICAL DEVICES, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant This Phase I STTR Grant Proposal requests $ support for WestFace Medical Device to construct and test the WestFace Imaging Adaptor in conjunction with Ruikang K Wang PhD and his laboratory at the University of Washington Utilizing optical coherence tomography OCT the patented OCT Adaptor USPTO Pats provides r ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health

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