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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. An Augmented Reality Sandbox for use in Early Elementary STEM Instruction

    SBC: Parametric Studio, Inc.            Topic: 91990020R0007

    This project will fully develop NEWTON-AR, an augmented reality (AR) application-based engineering, computer science, and STEM puzzle game for children in kindergarten to grade three. Intended for use in classrooms, after-school programs, and at home, NEWTON-AR will combine AR, engineering, simulation, making, and programming into a sandbox game where students create, modify, simulate, prototype, ...

    SBIR Phase II 2020 Department of EducationInstitute of Education Sciences
  2. Mol: An Interactive Learning Platform to Address Difficult Concepts in Organic Chemistry

    SBC: Substrate Interactive, Inc.            Topic: 500

    Abstract Concepts of organic chemistry are central to medicine and pharmacologyHoweverorganic chemistry represents a significant hurdle for sciencetechnologyengineeringand mathematics students in pre health tracksLow exam scores and high failure rates result from the enormous amount of informationcomplex chemical structures and dynamicsand processes requiring creativity and spatial thinkingThe cha ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Artificial intelligence-enabled, real-time communication software for optimizing clinical decision making during the allocation, procurement, and transplantation of donated organs

    SBC: Healthtech Solutions, Inc.            Topic: NLM

    Project Abstract for HealthTech Solutions Kidney transplantation is a clinically effective and cost effective treatment for patients suffering from end stage renal diseaseESRDand diabetesTwenty two patients die each day waiting for a transplant andof all deaths in the US could be prevented by organ transplantDespite the obvious clinical and cost effective advantages of kidney transplantationthere ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. An Automated Patient Chart Error Detection System for Radiation Therapy

    SBC: Infondrian LLC            Topic: 101

    Project Summary Abstract Every yearapproximatelysevere mistreatments happen in radiation therapyRadiation therapy lawsuits rank in the top third of all medical specialties with an average of $per claim settled or litigatedThe current method for detecting treatment errors is by a weekly patient chart checkwhere each treatment record is manually reviewed on a weekly basisThis labor intensive and ine ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Phase 1 cross over biodistribution study of [203Pb]VMT01 for single photon emission computed tomography (SPECT) and [68Ga]VMT02 for positron emission tomography (PET) imaging of stage 4 melanoma

    SBC: VIEWPOINT MOLECULAR TARGETING, LLC            Topic: 102

    SIGNIFICANCEMelanoma incidence is rising faster than any other cancer and metastatic melanoma is typically fatalResponses to targeted and immunotherapies can be remarkablebut low response ratesacquired resistanceand adverse side effects limit long term quality of life for these patientsThe overall response rate to all therapies remains dismally nearand theyear survival is andltPreclinical studies ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. MUC4/16 assay for the early diagnosis and management of benign and malignant pancreatic diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 300

    Abstract The goal of this Fast track application is to develop a non invasive diagnostic testbased on MUCand MUCmucinsthat can serve as an adjunct to cytological analysis of fine needle aspiratesFNAsfor accurate prediction of malignancy in patients with cystic pancreatic lesionsDue to asymptomatic nature and lack of methods for early detectionandgtof pancreatic cancerPCpatients present with an unr ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Novel Small Molecule Therapies for Skeletal Muscle Atrophy

    SBC: EMMYON, INC.            Topic: R

    PROJECT SUMMARYABSTRACT Skeletal muscle atrophy diminishes the health and quality of life of tens of millions of people in the US aloneFrequent causes of muscle atrophywhich often co exist in the same patientinclude agingmalnutritionmuscle disusecritical illnesscertain medicationsand a broad range of chronic illnesses including cancerheart failureCOPDdiabetesrenal failurecirrhosisrheumatoid arthri ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Seromic Mucin Signature for the Early Diagnosis of Pancreatic Cancer

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 102

    ABSTRACT Pancreatic cancerPCis an extremely aggressive malignancy with one of the worst prognoses of all cancersWith marked resistance to chemoand radiotherapiessurgery is the only curative optionIn patients with localized diseasecomplete surgical resection provides five year survival rate ofHoweverandgtof patients are diagnosed with unresectable primary tumors and or distant metastasisThe major c ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A Prognostic Blood Test to Monitor Pancreatic Cancer Treatment by MiRNA Profiling

    SBC: VAJRA INSTRUMENTS, INC.            Topic: 102

    Pancreatic ductal adenocarcinomaPDAChas ayear survival rate of less thanThe success in developing therapies for other cancers over the last two decades has not improved the dismal overall survivalOSrate for PDACIt is now becoming increasingly apparent that personalized medicine based on the genetics of a tumor will be essential for developing a treatment strategyThusthere is an urgent need to deve ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Next Generation Western for high-throughput and high-content protein analysis

    SBC: LI-COR, Inc.            Topic: 400

    Abstract The identification and quantification of specific proteins in complex samples are critical processes in discoveringunderstandingand ultimately addressingthe underlying nature of human health and diseaseThe western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno detectionDespite being widelyusedthe ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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