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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Goal Guide: A Web-Based Application for Self-Management of Goal Tracking

    SBC: ASSISTECH SYSTEMS LLC            Topic: N/A

    This is a Phase II project to develop and evaluate the effectiveness of a responsively designed web application, Goal Guide, that enables individuals with intellectual disabilities and autism to effectively manage self-defined goals for everyday living across personal, educational, and vocational life domains. Users will be able to easily enter goals, work with data for each goal, engage with info ...

    SBIR Phase II 2014 Department of Education
  2. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: Learning Ovations, Inc.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase II 2014 Department of Education
  3. Novel Single Well Avidity EIA to Determine Recency of HIV-1 Infections

    SBC: SEDIA BIOSCIENCES CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The objectives of this project are to develop a commercial single well HIV-1 Limiting Antigen Avidity EIA, developed in Phase I as a research tool, and establish its suitability for identifying recent HIV-1 infections on both a population an on an individual clinical basis as an aid to early intervention in acute infections. Such methods are needed for accurate ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Therapeutic Thrombin Analogs

    SBC: ARONORA INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary/Abstract Treatment of acute ischemic stroke (AIS) with the thrombolytic/antithrombotic agent tissue plasminogen activator (tPA, Activase(R)) is limited due to the potential for severe hemorrhagic side effects. The first symptoms of acute ischemia to tPA treatment ( time to needle ) can span hours, even in developed urban areas, since an establis ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. IGF::OT::IGF Novel siRNA-nanoparticle Platform for Treating Drug-Resistant HER2 Positive Breast Cancer

    SBC: PDX PHARMACEUTICALS, INC.            Topic: NCI

    Over one million women worldwide are diagnosed with breast cancer each year. Roughly 20% of all breast cancers overexpress the human epidennal growth receptor 2 (HER2-positive subtype). HER2-targeted therapies, including Herceptin and lapatinib, account for 55% of the breast cancer therapy market in 2011 (or $5 billion annually). Response to HER2-targeted therapies typically average about one year ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Covert Optically-Reporting Threat-Functionalized Nanomaterials

    SBC: VOXTEL, INC.            Topic: DTRA122003

    To address the limitations of diagnostic equipment for chemical and biological warfare agent threats, Voxtel proposes to further develop low-cost, rapid biological-threat-reporting optical nanomaterials for a tag-track-and-locate system to consistsing of five components: 1) nanocrystal nanobeacons, a series of covert threat-functionalized optical identifiers with near-infrared through short-wave i ...

    SBIR Phase II 2014 Department of DefenseDefense Threat Reduction Agency
  7. Chitosan Endoluminal Hemostatic Dressing

    SBC: HemCon Medical Technologies Inc            Topic: 400

    DESCRIPTION provided by applicant Perioperative hemorrhage remains the major complication of transurethral and open prostatic surgical procedures Significant blood loss from these procedures causes delayed healing and longer hospitalization which significantly increases the cost of patient care Moreover prolonged urethral catheterization due to significant post operative hematuria is one of ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Preclinical development of novel small molecule malaria drugs that overcome drug

    SBC: DESIGNMEDIX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The worldwide health problem created by malaria has been made more difficult by the spread of drug resistant parasites We have developed an orally available and inexpensive class of novel drugs that act against both chloroquine resistant and chloroquine sensitive malaria This project carries on preclinical development of a drug candidate that has been select ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A human cytomegalovirus-based immunotherapy for HIV-1

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION The ultimate goal of this project is to develop an immunotherapy for human immunodeficiency virus HIV based on a spread deficient cytomegalovirus CMV derived vaccine expressing andquot tailoredandquot antigens designed for maximal coverage of clade B epitopes In non human primate models rhesus CMV vectored vaccines demonstrated unprecedented protection against highly virulent ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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