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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Developmental Neurotox Assay using Scalable Neurons and Astrocytes in High Content Imaging

    SBC: ARUNA BIO, INC.            Topic: B

    There is unmet need for rapid, cost effective in vitro methods to identify chemicals that pose a hazard to the human brain. A number of in vitro assays utilizing primary cells have been tested in an effort to devise effective models to prioritize chemicals for further in depth toxicity studies. However, isolation of primary human neural tissue is cost and labor intensive, and cannot be produced in ...

    SBIR Phase II 2014 Environmental Protection Agency
  2. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Expanding small molecule functional metagenomics through shuttle BAC expression i

    SBC: INTACT GENOMICS INC            Topic: NIAID

    DESCRIPTION provided by applicant Hospital acquired microbial infections are the fourth largest killer in America taking lives and adding $ B to hospital costs The emergence of drug resistant microbes has further amplified public health concern Fungi are prolific producers of anti microbial secondary metabolites SM and since the turn of the century have provided of bioactive m ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A study to improve the fit of HIV prevention methods

    SBC: THEYFIT, LLC            Topic: NICHD

    DESCRIPTION provided by applicant A policy statement by the World Health Organization notes that the male latex condom is the single most efficient available technology to reduce the transmission of HIV and other sexually transmitted infections Unfortunately despite decades of condom promotion efforts condoms usage rates remain disappointingly low Between one third and one half of men ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. MIST System for Simultaneous Parallel Intracellular Delivery & Transfection

    SBC: OPENCELL TECHNOLOGIES, INC.            Topic: 400

    DESCRIPTION provided by applicant Alternative nanomaterial and gene transfer solutions are needed to access the potential held in intracellular imaging biopharmaceuticals gene therapy and stem cell research Delivery of small and macromolecules including nucleic acids drug molecules imaging agents peptides antibodies and enzymes into cells is criti ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Friends, Family, and Food: Interactive Virtual Environments for Children with Food Allergies

    SBC: VIRTUALLY BETTER INC            Topic: NICHD

    DESCRIPTION provided by applicant Pediatric Food Allergy FA is recognized as a serious public health concern that affects approximately percent of children with symptoms affecting multiple organ systems including skin the respiratory tract and the GI tract Food induced anaphylaxis which is a rapid potentially life threatening reaction can occur in more serious cases Despite the s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Pegasys VR: Integrating Virtual Humans in the Treatment of Child Social Anxiety

    SBC: VIRTUALLY BETTER INC            Topic: NIMH

    DESCRIPTION provided by applicant Anxiety disorders are the most common psychiatric disorders among youth with lifetime prevalence ranging between of the general population Among anxiety disorders social anxiety disorder SAD affects of all youth resulting in significant short and long term impairment including increased likelihood of substance abuse limited academic achievemen ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Personalized Assistive Technology to Improve Dementia Care at Home

    SBC: SimpleC, LLC            Topic: NIA

    DESCRIPTION provided by applicant This Fast Track SBIR application submitted by SimpleC of Atlanta Georgia requests funds to test our current behavior management technology for persons with dementia PWD the SimpleC Companion and to develop and test a new mobile tablet the SimpleC Wellness Coach in the in home aging in place market where the overwhelming majority of PWD receive their ca ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Promotora Program to Prevent Primary Tooth Decay in Low-income Latino Children

    SBC: KDH Research & Communication, Inc.            Topic: NIDCR

    DESCRIPTION provided by applicant KDH Research andamp Communication KDHRC proposes to develop and evaluate Dientes Fuertes Vida Sana DFVS a culturally competent program to prevent primary tooth decay in low income Latino children ages zero to six To effectively reach low income Latino children DFVS will train promotores de salud PS at Latino serving community based organizations CBO ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Direct RT-PCR detection of RNA pathogens in crude samples

    SBC: DNA POLYMERASE TECHNOLOGY, INC.            Topic: 200

    DESCRIPTION provided by applicant The objective of this application is to introduce a novel simplified low cost technology to address the broad need of detecting RNA pathogens directly in crude samples such as blood Traditional RT PCR requires purifying the RNA which increases the cost time and risk of cross contamination We intend to reduce or eliminate the purification step by producin ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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