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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Transdermal Naltrexone for Opiate Addiction and Alcoholism

    SBC: ALLTRANZ, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction. Naltrexone (NTX), an opioid antagonist, is currently used in oral tablet form to help maintain opio ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Novel method to create knockout rats using endonucleases and spermatogonial stem

    SBC: TRANSPOSAGEN BIOPHARMACEUTICALS, INC.            Topic: 200

    DESCRIPTION provided by applicant The laboratory rat is a preferred rodent model in pre clinical drug studies Their larger size facilitates procedures otherwise difficult in mice includng studies using instrumentation blood sampling and surgeries and allows for ten times the amount of tissue collection Although rats are often more suitable than mice for pharmacological toxicological phy ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Biological vector control reducing arboviruses, including Dengue and Chikungunya

    SBC: MosquitoMate, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant In the absence of effective approved drugs or vaccines vector control remains the only means of intervention for many against mosquito borne diseases This problem grows more complex with the recent establishment of multiple exotic mosquito species and mosquito borne pathogens Furthermore changing climate conditions are predicted to alter the traditional ra ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent fin ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Circulating Blood-Based Diagnostic for Mild Cognitive Impaired Victims

    SBC: ADVANCED GENOMIC TECHNOLOGY, LLC            Topic: NIA

    DESCRIPTION provided by applicant This project aims to generate blood tests for mild cognitive impairment MCI and conversion risk from MCI to full blown Alzheimerandapos s disease AD We have reported that systemic footprints increases in key micro RNA miR levels are identifiable in AD blood samples here we suggest that this is also true for MCI the pre AD phase Our recent ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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