Award Data

DESCRIPTION provided by applicant The ideal most effective tool for eliminating Plasmodium falciparum Pf the causative agent of of all malaria deaths is a highly effective vaccine that prevents blood stage infection and thereby prevents both disease and transmission Sanariaandapos s goal is to develop and commercialize a Pf sporozoite SPZ vaccine that prevents Pf blood stage infect ...

DESCRIPTION provided by applicant The proposed project will further develop marketable ELISA and lateral flow immunoassay diagnostics LFI in both monoplexed and multiplexed formats for the NIAID category A BSL filoviruses and will drive pre clinical development and validation for these diagnostics These assays will be used for diagnosis of Ebola virus EBOV Sudan virus SUDV and Marbu ...

DESCRIPTION provided by applicant Human rhinoviruses HRV are the leading cause of common colds and virus induced exacerbation of asthma and chronic pulmonary diseases In addition HRV can cause severe lower respiratory tract infections in children the elderly and immune compromised patients The economic burden of the common cold is estimated to be about $ B each year in the US in terms o ...

DESCRIPTION provided by applicant Autism is prevalent in children and impairing but early intervention has been shown to improve outcomes prompting recommendations for screening at both two year and month health check ups Detection of autism early is crucial but accurate screening tools have been elusive In Phase II a practical method of improving accuracy of M CHAT the most widel ...

DESCRIPTION provided by applicant Encephalitis and meningitis are potentially fatal diseases defined by acute inflammation of the brain or protective membranes covering the brain and spinal cord These diseases can be caused by viruses bacteria fungi parasites or amoeba and disproportionately affect children the elderly or the immunocompromised Viruses are the most common cause of enceph ...

DESCRIPTION provided by applicant Effective early intervention depends on reliable identification of risk for communication impairments as soon as possible Established infant risk factors for communication impairments include poor turn taking gestures receptive language commenting symbolic play and speech Although these risk factors can be detected by mos and reliably predict late ...

DESCRIPTION provided by applicant Improvements in pre hospital trauma life support in the past years have led to impressive enhancement in patient survival These achievements have come as the result of improved equipment transport logistics assessment treatment protocols and training of personnel in all levels of the care chain from the point of injury to th hospital One of the areas th ...

DESCRIPTION provided by applicant In this project we will develop a commercial resource for the automated analysis of brain anatomy based on MRI This product is based on the whole brain parcellation algorithm with the following unique features First it is based on a cutting edge multi atlas approach in which we will incorporate rich atlas resources from Dr Moriandapos s lab at the Johns ...

DESCRIPTION provided by applicant Asthma affects of US children and is a leading cause of ED visits hospitalization missed school suffering and death It disproportionately affects low income minorities This proposal seeks to overcome health care delivery barriers to implementation of national asthma guidelines both clinician failures to provide guideline based care and patient adheren ...

DESCRIPTION provided by applicant The goal of this Phase I Phase II Fast Track application is to develop and evaluate a simulation based product for training student affairs staff e g resident assistants RAs Greek life staff campus and housing security student conduct staff and academic advisors to assess and provide appropriate intervention to students who engage in risky drinking be ...