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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Next Generation Western for high-throughput and high-content protein analysis

    SBC: LI-COR, Inc.            Topic: 400

    Abstract The identification and quantification of specific proteins in complex samples are critical processes in discoveringunderstandingand ultimately addressingthe underlying nature of human health and diseaseThe western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno detectionDespite being widelyusedthe ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Mouse Stem Cell Research Using the Dracula Pipette

    SBC: GENESEARCH, INC.            Topic: 100

    Advanced approaches for genetic or epigenetic modification of embryonic stemEScellsincluding TALENZFNor CRISPR catalyzed genetic modifications or modulation of gene expression via small RNAssynthetic mRNAsor recombinant transcription factorshave revolutionized our ability to modify the cells from which novel mouse lines are producedIn contrastprocedures for utilizing these cells within the context ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Development of an Open Speech Signal Processing Platform

    SBC: SensorLogic, Inc.            Topic: NIDCD

    This proposal will create an open speech signal processing platform. The open computational framework will be used for developing algorithms that will help accelerate acoustic and hearing science research. It will permit researchers to more rapidly and easily test new algorithms with greater control, performance, and ease. Several example systems will be created to show that the platform can be ad ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of technologies to advance fast and accurate tools for measuring fluorescence in living cells, with emphasis on developing assays optimized for screening in neuronal cells and brain tissue

    SBC: MONTANA MOLECULAR LLC            Topic: 105

    Project SummaryMontana Molecular is in the business of developing and marketing genetically encoded biosensors for academic research and drug discovery in living cellsOur biosensors provide robust detection of crucial second messenger signalingincluding DAGPIPcAMP and Caon both fluorescence microscopes and the large installed base of automated plate readerswith metrics that match or surpass those ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Co-axial Microinjection System for Freezing and Biopsy of Early Embryos

    SBC: GENESEARCH, INC.            Topic: 100

    DESCRIPTION provided by applicant The Dracula Pipette is a co axial embryo microinjection tool with the injection pipette presented from inside the holding pipette Double nested tips seal against the surface of the spherical embryo when a vacuum is applied in the space between them This allows a portion of the nearside surface of an embryo to be held by vacuum while a glass pipette is passed ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Fast and Accurate Tools for Measuring Fluorescence in Living Cells

    SBC: MONTANA MOLECULAR LLC            Topic: 106

    DESCRIPTION provided by applicant Specific information about the state of second messengers in drug signaling pathways is key to understanding the mechanism of a drug within the cell The largest class of drug targets is the G Protein Coupled Receptor GPCR and over of all prescription pharmaceuticals target a GPCR These proteins are the focus of many drug discovery programs because they ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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