Award Data

We propose to develop reactive composite materials with sufficient strength and stiffness to serve as structural components for penetrating weapons and other munitions. The composites will consist of two materials that react with each other, in either oxidation-reduction (such as in a thermite) or bimetallic reactions. One component will be in the form of fiber, wire, or wire-mesh, within a bondin ...

DESCRIPTION (provided by applicant): Heart failure (HF) is a major health problem in the US and worldwide. Over 100,000 people in the US are diagnosed with end stage HF annually. Heart transplantation is performed in only 2% of these cases due to lack of available donor hearts. Mechanical left ventricular assist devices (LVADs, a type of artificial heart) can allow patients with severe HF to live ...

DESCRIPTION (provided by applicant): The program outlined in this application has been designed to accelerate the development and commercialization of a Glucagon Mini-Dose Pen to change the paradigm for treatment of moderate hypoglycemia in insulin-using diabetics. This research is directly relevant to the NIDDK which is explicitly interested in the development of innovative technologies for the p ...

DESCRIPTION (provided by applicant): This project is an evaluation of a novel device, the Air Barrier System (ABS), to reduce the risk of prosthesis- related surgical site infection in a multi-center clinical trial. The ABS shields surgical incisions intra-operatively by creating a field of high-purity air surrounding an incision that prevents airborne microorganisms from entering the incision. Pr ...

DESCRIPTION (provided by applicant): An estimated 300 million people worldwide are affected by asthma, causing up to 250,000 deaths per year1,2. Asthma is a personal and public, health and economic burden even in developed countries, where nearly 10% of the population loses substantial time away from work and school. The principal cause of asthma exacerbations, responsible for more than 70%3, is v ...

DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

DESCRIPTION provided by applicant Higher vegetable intake has been related to lower risks of diabetes cardiovascular disease several cancers and obesity adiposity later in life Yet children are eating vegetables well below recommended amounts Parents are important influencers on the dietary intake of young children but they commonly report difficulty getting their child to eat vegetables ...

DESCRIPTION provided by applicant With the advent of rapid bench top sequencers such as the PGM and MiSeq the potential to transform cancer diagnosis and patient care is great Although sequencing instrumentation has become relatively affordable the need for NGS data analysis and interpretation still remains a big hurdle to the adoption of NGS based assays for many research and clinical labor ...

DESCRIPTION provided by applicant Nearly billion people mostly in Africa South East Asia and Latin America have inadequate iodine nutrition Pregnant women and children are most at risk from iodine deficiency disorders IDD which occur as a range of abnormalities including hypothyroidism which impairs mental development in the fetus and in infants Iodine deficiency disorders have been g ...

DESCRIPTION provided by applicant The purpose of this Phase II Small Business Technology Transfer STTR project is to complete development and evaluate usability and effectiveness of the Wraparound Team Monitoring System Wrap TMS a web based electronic behavioral health information system EBHIS for the most widely implemented care coordination model in childrenandapos s behavioral healt ...