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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Access Language Arts

    SBC: Attainment Co., Inc.            Topic: N/A

    Purpose: Instruction in English Language Arts (ELA) for students with severe intellectual disabilities and autism can be challenging, as these students often do not have the skills to engage with text. In recent years, special education experts have proposed a comprehensive approach to supporting students with intellectual disabilities and autism in ELA, centered on strategies including word ident ...

    SBIR Phase II 2014 Department of Education
  2. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Toxoid adjuvant CRM197 production in a stable reduced genome E. coli strain

    SBC: SCARAB GENOMICS, LLC            Topic: NIAID

    DESCRIPTION provided by applicant CRM is an inactive form of diphtheria toxin that when conjugated to a vaccine antigen enhances immunity to generate long lasting vaccination against the antigen Conjugate vaccines containing CRM are common and there are currently seven CRM containing conjugate vaccines on the market The top selling vaccine the CRM containing conjugate vaccine P ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Continuous Chromatography Device to Economically Purify Clinical-grade Antibodies

    SBC: Semba Biosciences Inc            Topic: 102

    DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Antibacterial molecular coatings pre-fabricated for biologic wound dressings

    SBC: IMBED BIOSCIENCES, INC            Topic: NIAMS

    DESCRIPTION provided by applicant Clinical infections in burn trauma and surgical wounds represent a huge economic and health care burden In the U S there is a infection rate in surgical wounds and up to a rate in burn wounds The current standard of care is intensive and expensive involving frequent topical application of antimicrobials twice daily with painful dressing changes ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Electrode Arrays for Bloodless Liver Resection and Tumor Ablation

    SBC: MEDICAL ENGINEERING INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Both primary and metastatic liver cancer is common in the US and worldwide The standard treatment for liver cancer is liver resection where part of the liver containing the tumor is surgically removed This operation is associated with considerable blood loss typically between L Blood loss is adversely associated with patient morbidity and survival ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Structural bioinformatics software for epitope selection and antibody engineering

    SBC: DNASTAR, INC.            Topic: 100

    DESCRIPTION provided by applicant Therapeutic monoclonal antibodies bind to specific regions of proteins called epitopes which elicits cellular responses Traditional antibody discovery processes require laborious and expensive screening experiments so computational approaches that predict epitopes and accelerate antibody discovery are in high demand Structure based antibody design is also i ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Computerized Screening for Comorbidity in Adolescents with Substance or Psychiatr

    SBC: KOBAK, KENNETH A            Topic: 104

    DESCRIPTION provided by applicant This Phase II SBIR grant is a follow up to the Phase I SBIR grant andquot Computerized Screening for Comorbidity in Adolescents with Substance or Psychiatric Disorders andquot During Phase I parent and adolescent self administered computerized versions of the psychiatric interview the Kiddie Schedule for Affective Disorders and Schizophrenia KSADS were de ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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