You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
Iomab-ACT: A phase I/II study of 131-I apamistamab targeted lymphodepletion followed by CD19-targeted CAR T-cell therapy for patients with relapsed or refractory B-ALL or DLBCL
SBC: Actinium Pharmaceuticals, Inc. Topic: 102ABSTRACT Despite treatment advances, the prognosis of adult patients with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) and R/R diffuse large B-cell lymphoma (DLBCL) remains poor. Autologous T- cells modified to express a CD19-targeted chimeric antigen receptor (CAR T-cells) produce durable responses in subgroups of these patients, which has led to FDA approval of two su ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Controlled-release Microbeads to Replace Growth Factors in Fetal Bovine Serum
SBC: STEM CULTURES LLC Topic: 400Scientific Abstract: The frequent use of fetal bovine serum (FBS) to support cell cultures is challenged by lot-to-lot variability, supply constraints, pathogen contaminants and ethical questions. These issues have increased significance due to the burgeoning use of FBS in cell research and therapy development. FBS has been used for over a century to culture cells, but with the need to define cult ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
The Assessment of Smart Phone Everyday Tasks (ASSET): A new IADL test for early AD
SBC: RIP ROAD, INC. Topic: NIAProject SummaryImpairment in instrumental activities of daily living (IADL) is a hallmark of Alzheimer’s disease (AD) dementia and a major source of patient and caregiver burden. Similarly to cognitive changes in AD, subtle difficulties in IADL may begin even before the stage of amnestic mild cognitive impairment (MCI). Recently, greater emphasis has been placed on preclinical AD, which consists ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
A Disease-Modifying Protein Therapeutic for the Treatment of COPD
SBC: VERRA THERAPEUTICS LLC Topic: NHLBIPROJECT SUMMARY Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide at 3.23 million (2019), while nearly 400 million suffer its effects. COPD is a heterogeneous, multi-phenotypic disease with lung damage derived from smoking, vaping, cooking, forest fires, pollution, chemical exposure, and numerous occupational hazards (e.g., 1st responders, military, agricul ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of a Molecular Diagnostic to Identify Dangerous Intracranial Aneurysms
SBC: NEUROVASCULAR DIAGNOSTICS, INC. Topic: 103Project SummaryIntracranial aneurysm (IA) rupture is the primary cause of non-traumatic subarachnoid hemorrhage, a catastrophic event that carries high rates of mortality (rt50%) and permanent disability (rt50% among survivors). When an unruptured IA is discovered, clinicians face the difficult decision of whether or not it should be treated. Since rupture rates are low (risk of rupture ~ 0.5-1% p ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Non-Clinical Pharmacology of CX-01
SBC: Ceramedix Holding, LLC Topic: NIAIDDevelopment of radiation medical countermeasures (MCM) has become a national security priority owing to such threats as radiological dispersal devices (i.e., “dirty bomb”) and nuclear accidents, which may be caused by extreme weather (such as occurred in Fukushima, Japan in 2011). Radiation exposure can be potentially lethal via the hematopoietic-acute radiation syndrome (H-ARS) and the gastro ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
HaloFilm: a spray-on, re-chargeable, re-applicable antimicrobial coating
SBC: Halomine Inc. Topic: NIAIDProject Summary/Abstract In the US, about 1.7 million Healthcare-Associated Infections (HAls) occur in hospitals each year, resulting in 99,000 deaths and an estimated $20 billion in healthcare costs. According to previous reports, as much as one third of HAI cases can be attributed to environmental surfaces, namely “high touch” surfaces (e.g., bed rails, machine buttons, equipment), in hospit ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing a novel EEG-based index for evaluating amyloid and tau burden in Alzheimer's Disease
SBC: Spark Neuro Inc. Topic: NIAPROJECT SUMMARY Alzheimer’s disease (AD) is a progressive, neurodegenerative condition that impacts 44 million people globally. It is the most common cause of dementia—accounting for 80% of all dementia diagnoses—and predominantly affects older people. To date, AD has no cure. Thus, it is imperative to diagnose patients as early as possible to maximize the efficacy of symptom management stra ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
In vivo high-definition 3D corneal imaging
SBC: LighTopTech Corp. Topic: NEIThe cornea, the outermost window of our visual system, is vulnerable to various types of infections and diseases. Corneal disease is one of the leading causes of visual deficiency and blindness, and is considered the second major cause of blindness in developing countries. There are nearly 5 million bilaterally corneal blind persons worldwide, and an estimated 23 million people affected by unilate ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
IL-10NanoCap® for Therapy of Familial Adenomatous Polyposis
SBC: THERAPYX, INC. Topic: 300Abstract This SBIR Phase IIb proposal builds on the success of our Fast-track award supporting the pre-clinical development of FAPXIL, an oral sustained-release micro-particulate formulation of Interleukin-10 for the treatment of Familial Adenomatous Polyposis (FAP). The Phase I portion of our Fast-track project provided validation of our large-batch methods and activity in a clinically-relevant m ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health