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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. AUTOMATED DROPLET MONITORING SYSTEM

    SBC: CREARE LLC            Topic: NIDA

    Modern drug discovery methods require the use of automated liquid handling and dispensing systems for screening large numbers of candidate compounds to identify new drug candidates The use of these high throughput methods has been made possible by the development of automated systems that can dispense extremely small volumes of reagent at high speed However many of the reagents used in testing ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. IGF OT IGF MULTIPLEXED BIOMARKER ASSAY FOR CLASSIFICATION OF PATIENTS WITH SYSTEMIC SCLEROSIS

    SBC: CELDARA MEDICAL, LLC            Topic: NIDA

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Stroke Treatment by Chemically-induced Hypothermia

    SBC: JT Pharmaceuticals, Inc.            Topic: 101

    DESCRIPTION provided by applicant Stroke is a leading cause of human death and disability in the United States while clinical therapy for acute stroke is limited and unsatisfactoy The many failures in clinical trials strongly endorse the idea that to battle this multifaceted bran disorder novel strategies that target multiple cell types and different mechanisms are needed to achieve therapeut ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Optical imaging for radiation therapy dose verification on patients

    SBC: DoseOptics LLC            Topic: 102

    DESCRIPTION provided by applicant For the first time it is possible to directly visualize a radiation beam incident upon a patientandapos s tissue in real time using Cerenkov emission imaging This imaging could transform the ease for verifying delivery in radiation oncology and allow on the fly reporting recording and correction of replanning needs or delivery errors In a field wher there ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Therapy of transplantation-induced oxidative injury using polymeric antioxidants

    SBC: CELDARA MEDICAL, LLC            Topic: 400

    DESCRIPTION provided by applicant Ischemia reperfusion I R injury during renal transplantation surgery is responsible for oxidative stresses which result in immune activation and graft rejection We are developing an antioxidative therapy that we have already shown to be highly efficacious in ameliorating damage from oxidative stress in various in vitro models as well as I R models of kidney ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Developing the Dietary Inflammatory Index for Clinical Application

    SBC: Connecting Health Innovations, LLC            Topic: 300

    DESCRIPTION provided by applicant A large persuasive and ever increasing body of evidence links chronic inflammation to virtually all of the chronic diseases that cause the majority of disability and death in the U S including diabetes cardiovascular diseases CVD and cancer Diet plays a central role in the regulation of chronic inflammation However until we developed the dietary infl ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Diagnostic Biomarkers to Predict Individual Propensity to Diabetic Complications

    SBC: PREVENTAGE HEALTHCARE, LLC            Topic: 200

    DESCRIPTION provided by applicant The diabetes epidemic and the devastating complications that accompany it have created an unprecedented worldwide medical crisis It is primarily the complications of diabetes including kidney failure blindness cardiovascular disease and neuropathy that accounts for the $ billion spent in in the US A significant problem for doctors who treat diabe ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Closed Loop MAS DNP NMR at K for Affordable Dramatic Gains in S N

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    DESCRIPTION provided by applicant NMR is arguably the most powerful analytical technique for structure determination and function elucidation in molecules of all types but there are complex challenges for biological macromolecules Dynamic Nuclear Polarization DNP with Magic Angle Spinning MAS has recently demonstrated S N gains of up to two orders of magnitude at K the lower tempera ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Assessment of lung function in neonates and infants

    SBC: XEMED LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Although lung disease is a major cause of morbidity in children the forced breathing maneuvers required for assessing disease spirometry cannot be performed by young children Thus characterizing the activity or monitoring the severity of pediatric lung disease in younger children is primarily qualitative based upon parental reports with little quantitati ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Neurotensin Fragment for Neuropathic Pain

    SBC: JT Pharmaceuticals, Inc.            Topic: 101

    DESCRIPTION provided by applicant Neuropathic pain management is a major unmet clinical need Classically used medications opioids and non opioids NSAIDs have major side effects associated with their use and many individuals do not respond to any medications Neuropathic pain drugs with novel mechanisms of action are being sought as alternatives however the only novel FDA approved drugs w ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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