Award Data

Video Demonstration of the Phase I Prototype: https://www.youtube.com/watch?v=PsvXXII2zzw&index=5&list=PLVHqsnePfULrUf_-HwtRfwEYsb9patGd- Purpose: This project will develop and test Eco, an online multiplayer virtual environment and game designed to enhance middle school students' knowledge of ecology and environmental literacy. This is important because according to the 2011 National Assessment ...

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DESCRIPTION provided by applicant Doppler ultrasound is relied upon as the primary and often the only test used to diagnose vascular pathology Because variations in technical skill directly impact surgical referral decisions there is a strong clinical need to ensure that provides both attain and maintain skills in this procedure The problem we address is the lack of a quantitative or standar ...

DESCRIPTION provided by applicant Pluripotent stem cells have the potential to treat diseases affecting almost every organ system However their clinical use is limited by host rejection due to differences in the diverse Major Histocompatibility Complex MHC genes In the past this problem has been addressed by using MHC matched donors and or dangerous immunosuppressive drug regimens Here ...

DESCRIPTION provided by applicant Stroke is a leading cause of human death and disability in the United States while clinical therapy for acute stroke is limited and unsatisfactoy The many failures in clinical trials strongly endorse the idea that to battle this multifaceted bran disorder novel strategies that target multiple cell types and different mechanisms are needed to achieve therapeut ...

DESCRIPTION provided by applicant Current practice in the USA for inoperable esophageal cancer is a palliative treatment using metal stent for end stage cancer patients Outside the USA especially in far east countries including China and Korea there have been reported clinical benefits of attaching sealed sources such as prostate seeds to the outside of an esophageal stent Although sim ...

DESCRIPTION provided by applicant We are developing the Indicator Cell Assay Platform iCAP a broadly applicable and inexpensive platform for blood based diagnostics that can be used for early detection of disease and as a companion diagnostic for drug development The iCAP uses cultured cells as biosensors capitalizing on the ability of cells to respond differently to signals present in th ...

DESCRIPTION provided by applicant Next Generation Sequencing NGS technologies provide a key mechanism in the expansion of precision medicine wherein treatments are designed based on the genetics unique to an individual patientandapos s illness A long standing and effective application of this concept has been in the clinical arena of hematopoietic cell transplants HCTs where for over ...

DESCRIPTION provided by applicant Prostate cancer PCa is the most commonly diagnosed cancer and second leading cause of cancer death in American men The utility of the widely accepted diagnostic test for PCa the PSA test has come under severe scrutiny as only of men with PCa have levels that fall within the current PSA reference range Elevated PSA levels are not correlated well wit ...