Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. The Intelligent Brace: A Compliance Monitoring System for Scoliosis

    SBC: Liberating Technologies, Inc.            Topic: N/A

    Scoliosis, a condition where there is lateral curvature of the spine, affects an estimated 6 million people in the United States. There is widespread use of bracing for treatment of adolescent idiopathic scoliosis, and recent studies have begun documenting its efficacy. These studies have indicated that user compliance is a large, yet largely unquantified, factor in successful outcomes. There are ...

    SBIR Phase II 2014 Department of Education
  2. Therapeutic Intermittent Compression Socket

    SBC: Liberating Technologies, Inc.            Topic: N/A

    The purpose of this project is to develop a device that provides rapid intermittent compression to the residual limb of amputees that do not have good blood flow in their limbs. The device will be built into the prosthetic socket to provide the user with portable therapy throughout the day, which will free the user from being confined to a chair for up to six hours each day to receive the prescrib ...

    SBIR Phase I 2014 Department of Education
  3. Socrative Learning Network

    SBC: Socrative Inc            Topic: N/A

    The project team is developing a prototype of the Socrative Learning Network, a website for teachers to share information to guide instructional practice. The website will support Socrative’s existing 600,000 registered teachers in creating, sharing, searching, and filtering assessments by content, grade, or user, with a mechanism for commentingedu on and editing questions. Pilot research in Pha ...

    SBIR Phase I 2014 Department of Education
  4. Expanding Supports for Data-Driven Language Instruction

    SBC: LingoJingo            Topic: N/A

    The project team will strengthen the functionality of Lingo Jingo, an on-line foreign language teaching and learning website, by adding lesson development capabilities, management tools, analytic capabilities, and activities aligned with commonly used language textbooks. The product will be used by middle and high school teachers to develop or modify classroom instruction, assign lessons, and prov ...

    SBIR Phase I 2014 Department of Education
  5. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD, LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of PAR2 Inhibitors for the Treatment of Nonalcoholic steatohepatitis

    SBC: OASIS PHARMACEUTICALS, LLC            Topic: NIDDK

    DESCRIPTION provided by applicant Non alcoholic steatohepatitis NASH is characterized by fatty changes in the liver with inflammation and hepatocellular injury that in advanced stages leads to fibrosis and cirrhosis and high mortality rates NASH is frequently associated with other common metabolic abnormalities such as insulin resistance and visceral obesity Liver transplantation is curren ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Small Molecule Inhibitors of trans-Translation with Broad Spectrum Antibacterial

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Because of the emergence of resistance to known antibiotics there is a critical need for new antibacterial agents especially against Gram negative pathogens trans Translation is a biochemical pathway that is essential to many bacterial species including Neisseria gonorrhoeae Shigella flexneri and Mycoplasma spp A high throughput assay of trans translatio ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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