Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD, LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Backbone Degradable Polymer-drug Conjugates for the Treatment of Ovarian Cancer

    SBC: TheraTarget, Inc.            Topic: NCI

    DESCRIPTION provided by applicant The purpose of this Phase II STTR project is to develop a polymeric system for the combination delivery of two antineoplastic agents gemcitabine and paclitaxel Based on the successful results of the STTR Phase I award this Phase II proposal details the rationale and research plan for the synthesis and evaluation of in vivo efficacy of two novel macromolecula ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Cost-effective MHz rate Optical Coherence Tomography for biomedical applications

    SBC: WASATCH PHOTONICS, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant During this SBIR Phase I project we propose to build and test in phantoms a prototype of an innovative cost effective Optical Coherence Tomography OCT system with a X increase in acquisition rate compared to commercially available systems Further development may add an additional X increased acquisition rate for a total of X Current market demand for ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Reversal of Myocardial Infarction by Localized Stimulation

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Blocking a novel cytokine signaling pathway for the treatment of rheumatoid arthr

    SBC: NAVIGEN, INC.            Topic: NIAMS

    DESCRIPTION provided by applicant In spite of remarkable progress in management of rheumatoid arthritis RA a devastating autoimmune disease that affects million Americans causing chronic inflammation of joints and surrounding tissues the gap of unmet needs in this therapeutic field remains wide open First of all almost of the patients do not respond adequately to the most advanced ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Allergens and Induced Asthma: Eradicating Indoor Allergens from Dust Mites (Phase

    SBC: CarboNix LLC            Topic: NIEHS

    DESCRIPTION provided by applicant The mission of CarboNix LLC is the clinically effective abatement of common indoor allergens that cause allergic reactions and frequently induce asthma especially in economically disadvantaged children CarboNix LLC proposes a Phase II SBIR research program that will result in commercialization of a new service business for abating multiple indoor allergens k ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Cryopreservation of Engineered Tissue Equivalents

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: 300

    DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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