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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Aerosolized platinum nanoparticle chemotherapy for lung cancer
SBC: HYLAPHARM LLC Topic: 102Significance Lung cancer is the leading cause of cancer deaths with over new diagnoses annually Survival rate of lung cancer patients is correlated with the extent of lymph node metastasis Standard care includes chemotherapy radiation and or surgery Cisplatin is a first line chemotherapy for lung cancer but systemic intravenous IV delivery is confounded by various toxicities rena ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
he 3D Platelet Bank: A Clinical-grade, Scalable, 3D Microbioreactor Bone Marrow Mimetic for Platelet Production
SBC: KIYATEC, LLC Topic: NIBIBProject Summary Abstract The transfusion of platelets is a major component of the treatment of cancer patients undergoing chemotherapy and or bone marrow transplantstrauma patientssepsisand battlefield injuriesHoweverdue to a complete reliance upon donors as the only current approved source of plateletsand the strictshort shelf life and storage conditions of donorderived plateletscurrent supplies ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Polo box PLK Inhibitors Target Tumors Resistant to ATP Competitive Compounds
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIPolo like kinase PLK is a central player in regulating entry into and progression through mitosis Many studies have validated PLK as an anti tumor drug target and its inhibition is potently anti proliferative to cancer cells However recent data suggests that there are two major disadvantages of the conventional approach to blocking the kinase activity of PLK First both general kinome ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Scaffold to Promote Skin Regeneration
SBC: FirstString Research, Inc Topic: NIAMSPROJECT SUMMARY Dermal scarring affects more than million people worldwide annually over million people are injured in motor vehicle accidents over million patients are severely burned and thousands of warriors are wounded in military blasts In severe burns more than of patients develop hypertrophic scar contraction which leads to hypertrophic scar contractures HSc HSc a ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes
SBC: DOTY SCIENTIFIC, INC. Topic: NIAA Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes Abstract There has been explosive growth in interest in Dynamic Nuclear Polarization DNP with Magic Angle Spinning MAS over the past five years because it has demonstrated S N gains exceeding two orders of magnitude at K compared to conventional MAS NMR and non spinning NMR of biological macro ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Ice Free Vitrification and nanowarming of large cartilage samples for transplantation
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NIAMSResurfacing of articular cartilage with cold stored osteochondral allografts is employed clinically for repair of trauma and osteoarthritis induced articular cartilage surface damage Chondrocyte viability of transplanted articular cartilage is accepted as one of the determinants of outcome following osteochondral allograft transplantation We have previously developed an ice free vitrification me ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Precision Microspheres for Transtympanic Delivery of Ganciclovir for CMV Infection
SBC: ORBIS BIOSCIENCES, INC. Topic: YPROJECT SUMMARY Current approaches to treat sensorineural hearing loss SNHL in newborns suffering from congenital cytomegalovirus CMV infection rely on off label systemic antiviral therapy requiring high dose long duration treatment with demonstrated hematologic toxicity carcinogenicity and teratogenicity Furthermore it is unknown whether systemic delivery of antivirals maintain inner e ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Topical HSP90 Inhibitor (CTXT-102) in the Treatment of Mild to Moderate Plaque Psoriasis
SBC: Regranion, LLC Topic: NIAMSPROJECT SUMMARY Psoriasis is a chronic inflammatory skin disease affecting approximatelymillion Americans that can become debilitating and severely impact quality of lifeWhile an estimatedof patients suffer moderate to severe disease forms that require systemic therapy with immune suppressants and ultraviolet phototherapythe majorityof patients exhibit milder symptomsFor these patientstopical agen ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
An HXYZ-g HR-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations
SBC: DOTY SCIENTIFIC, INC. Topic: 400An HXYZ g HR Fast MAS probe for Dramatically Improved Biomolecular Structure Determinations AbstractLiquid state NMR spectroscopy is arguably one of the best tools for structure determination for soluble proteinsThe method provides atomic resolution for modest molecular weight proteins and or their complexesThe method begins to have difficulty when the molecular weight of the system causes slow mo ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
SBIR Phase II: High-capacity Multimodal Anion-exchange Membranes for Purification of Biologics
SBC: Purilogics, LLC Topic: 400Project Summary This SBIR Phase II project will address the need for column chromatography products that can simplify the purification process for therapeutic biologics and increase purification speedThe rapid pace of biologics developmentdriven in part by growth of emerging markets such as personalized medicinehas increased the demand for affordable and fastsmall batch production runs in multi pr ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health