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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Akt Inhibitors to Treat Ewing's Sarcoma

    SBC: Acenta Discovery, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Novel drugs that improve overall survival with decreased morbidity are critical in the war on cancer. Acenta Discovery Inc. has partnered with the Toretsky Lab of the Lombardi Cancer Center to create and preclinically evaluate novel inhibitors of the protein Akt. An Akt inhibitor would have tremendous value in improving the lives of patients with many types ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Antimicrobial-releasing gels for preventing infection in total joint arthroplasty

    SBC: Sonoran Biosciences, Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Orthopaedic Surgical Site Infections (SSIs), including Prosthetic Joint Infections (PJIs), are an extremely costly health care problem, illustrated by the 70,000- 114,000 average total cost per case to treat more than20,000 hip and knee replacement infections in the US each year. When a prosthetic joint becomes infected following arthroplasty, organisms form ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. AN ULTRASONIC NEURAL STIMULATOR

    SBC: PHOENIX BIOTECH, INC.            Topic: N/A

    A remarkable and unexpected interaction effect between high frequency ultrasound energy and bioelectrically excitable tissue will be employed to the development of a line of advanced microstimulators for medical neurogenic applications An excised nerve preparation as well as hippocampal tissue slices of the rat brain will be used as physiologic models for further study of the ultrasound interactio ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  4. Application of PPODA QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Application of PPODA-QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    PROJECT SUMMARY/ABSTRACTA cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain. Often going unnoticed and untreated, an aneurysm can cause a sudden and catastrophic hemorrhage or stroke. Approximately 15 % of patients die from an aneurysm rupture even before receiving medical attention and 25 % of patients die despite medical treatment. Patie ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A Predictive Diagnostic System with Self-Learning for Space Mechanisms

    SBC: SPACEWORKS, INC.            Topic: MDA04T022

    SpaceWorks and the Georgia Institute of Technology propose an integrated predictive diagnostic system for evaluating the condition of spacecraft moving parts. Specific mechanisms to be addressed include reaction and momentum wheels, gimbals, flywheels and cryocoolers. To accurately estimate the remaining life of components, an intelligent diagnostic and prognostic monitoring and computational st ...

    STTR Phase I 2004 Department of DefenseMissile Defense Agency
  7. A Process That Rapidly Produces Be/Be Alloys in Net Shape at Low Cost Without Exposure of the Workforce

    SBC: ATS-MER, LLC            Topic: MDA04T011

    Beryllium and beryllium alloys are strategic to many defense/aerospace applications, but whose use is limited due to current and anticipated more stringent health and safety concerns which result in long lead times for fabrication and very high cost. An innovative approach that reduces fabrication time to a matter of hours to a few days results in low cost and produces net shapes without exposure ...

    STTR Phase I 2004 Department of DefenseMissile Defense Agency
  8. B7-H3-Targeted Contrast Agent for Ultrasonic Imaging of Breast Cancer

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    ABSTRACT Breast cancer is the second leading cause of cancer deaths in women in the United States and early detection can help improve survival While mammography is the current first line imaging technique for early breast cancer detection its diagnostic accuracy is limited in women with dense breast tissue Ultrasound is often performed as a second line test in women with dense breast tissue H ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Biomimetic Wound Healing Devices to Close Diabetic Wounds

    SBC: PROTEIN GENOMICS INC.            Topic: NIDDK

    The long term objective of this project is the synthesis and assembly of wound healing devices that mimic as closely as possible the biochemical and mechanical characteristics of healthy human skin The proposed research would focus on the synthesis of membranes containing electrospun human recombinant tropoelastin and collagen mixtures The ratios of the two molecules and the spinning condition ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. BROAD SPECTRUM BETA-LACTAMASE INHIBITORS

    SBC: ALAMX, LLC            Topic: N/A

    DESCRIPTION (Adapted from the application): Penicillin-resistant bacteria pose a serious threat to human welfare. This project will generate new products designed to defeat resistant microorganisms. The most prevalent cause of bacterial resistance involves the destruction of the antibiotic with the enzyme B-lactamase. There are more than 255 known B-lactamases, whi ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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