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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A2A receptor blockade for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIAID

    SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. AC5 Inhibitor for Obesity

    SBC: VASADE BIOSCIENCES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop a drug that will be therapeutic for obesity and diabetes and improve exercise tolerance. Obesity, diabetes and exercise are inextricably linked such that an agent that improves exercise tolerance or prevents obesity or the development of diabetes will likely have a therapeutic role in all three conditions. Obesity is a gl ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Advanced Absorbance Detection for the AUC

    SBC: AVIV BIOMEDICAL INC            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this STTR is to produce a commercially available rapid-scan absorbance optical detection system for XLA/I analytical ultracentrifuges. The currently available absorbance optical system provided by the analytical ultracentrifuge manufacturer is not optimized for sedimentation velocity analysis, the most commonly used analytical ultracentrifugation ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Cannula Development for Coronary Sinus Access

    SBC: STRATEGIC PACING SYSTEMS LLC            Topic: NHLBI

    DESCRIPTION provided by applicant This Phase STTR will develop novel techniques for coronary sinus access The coronary sinus provides unique anatomic and physiologic proximity to all four cardiac chambers and the coronary circulation For example the coronary sinus is used for left ventricular lead insertion for biventricular pacing or cardiac resynchronization Mor than such implan ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A Hemoadsorptive Device for the Treatment of SIRS

    SBC: MEDASORB TECHNOLOGIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed project is to develop a hemoperfusion device for the clinical treatment of sepsis and other conditions related to the Systemic Inflammatory Response Syndrome (SIRS). RenalTech International and Dr. John Kellum of the University of Pittsburgh have completed promising in vitro and in vivo laboratory studies in several mode ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. A MECHANICAL/NEURAL LIMB PROSTHETIC INTERFACE

    SBC: ORTHOGEN LLC            Topic: N/A

    DESCRIPTION (Provided by Applicant): Each year over 6,100 Americans undergo upper limb amputation requiring the use of prosthetic devices. With current devices, the patient is unable to mechanically and electrically control the prosthetic to mimic normal function. When nerves are severed or disrupted, the information for control is still present. A better, more natural control of the prosthesis co ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  7. A MECHANICAL/NEURAL LIMB PROSTHETIC INTERFACE

    SBC: ORTHOGEN LLC            Topic: N/A

    DESCRIPTION (Provided by Applicant): Each year over 6,100 Americans undergo upper limb amputation requiring the use of prosthetic devices. With current devices, the patient is unable to mechanically and electrically control the prosthetic to mimic normal function. When nerves are severed or disrupted, the information for control is still present. A better, more natural control of the prosthesis co ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  8. A New Class of Polymer Nanocomposites Using Surface Passivated Reactive Nanoparticles

    SBC: NEI CORPORATION            Topic: N/A

    "Building upon Fraunhofer Center's recently developed process of producing reactive nanoparticles (e.g., metals, carbides and nitrides) at high rates in a pristine environment, and Nanopowder Enterprises Inc.'s technology of dispersing nanoparticlesuniformly as a second phase in a polymer matrix, we propose to develop a generic technology for fabricating polymer nanocomposites, wherein the dispers ...

    STTR Phase I 2002 Department of DefenseMissile Defense Agency
  9. A Novel HIV-1 Latency System for Drug Discovery

    SBC: PTC THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Highly active antiretroviral therapy (HAART) has had an important impact upon morbidity and mortality from AIDS. Although HAART results in a remarkable suppression of HIV-1 replication in infected patients, it does not provide for elimination of the virus even after years of suppressive therapy. Contributing to the lack of viral clearance is the presence of lat ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. A practical and versatile high resolution D dosimetry system for clinical use

    SBC: HEURIS INC.            Topic: 102

    Quality assurance QA is a critical component of radiation oncology that ensures both effective treatment delivery and patient safety Over the last decade dQA is now particularly important asramatic innovations in treatment delivery technologiesy have led to increasingly sophisticated and complex treatments that are difficult to adequately verify with conventional dosimetric verification system ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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