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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Accurate Prostate Cancer Diagnosis for Active Surveillance Patients Using a Novel

    SBC: ProDevice Medical Supplies and Equipment LLC            Topic: NCI

    Project Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to confirm that the patient has no areas of higher-risk prostate cancer. For most patients who underwent ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Acoustic Counter Detection Tactical Decision Aid

    SBC: Ocean Acoustical Services And Instrumentation Systems Inc            Topic: N14AT016

    In this STTR, OASIS Inc, with partners the Massachusetts Institute of Technology (MIT) and the Applied Physics Laboratory University of Washington (APL-UW) proposes to develop an innovative, interactive submarine acoustic counter detect TDA for use by the Submarine Mission Planners, within the AN/BYG-1. Communicating the environmental and tactical uncertainty is of primary importance when present ...

    STTR Phase I 2014 Department of DefenseNavy
  4. Acoustic Counter Detection Tactical Decision Aid

    SBC: Kern Technology Group, LLC            Topic: N14AT016

    In order to maintain acoustic advantage, submarine crews need to assess acoustic vulnerability for historical and planned tracks and own ship noisy evolutions. A TDA or TDAs that produce acoustic advantage and vulnerability overlays for the geographic plot are essential to this. Our Phase I effort will develop a MATLAB-based TDA tool engine that when provided with the required inputs (own ship, en ...

    STTR Phase I 2014 Department of DefenseNavy
  5. Active Combustion Control of Augmentor Dynamics using Robust High-Frequency Energy Deposition

    SBC: Physics, Materials, and Applied Mathematics Research L.L.C.            Topic: N14AT004

    Combustion instability, or screech, occurs in many modern gas turbine systems, and is due to the complex physical coupling of the acoustic resonances in the combustion chamber with fluctuations in the heat release of the combustion process. These instabilities can produce large pressure fluctuations that can be severe enough to damage engine hardware. Next-generation gas turbines will increase the ...

    STTR Phase I 2014 Department of DefenseNavy
  6. A daily client check-in system for outpatient substance abuse treatment

    SBC: COG ANALYTICS, LLC            Topic: NIDA

    Abstract Alcohol and illicit drug use remain highly prevalent in the US, and epidemiological surveillance surveys estimate that over 20.6 million individuals (~ 8% of the US population) meet standard diagnostic thresholds for substance use disorders (SAMHSA, 2011). Outpatient substance abuse treatment is the predominate method of treatment in the US for SUDs, typically involving intermittent cont ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Adaptive Management and Mitigation of Uncertainty in Fusion (AMMUF)

    SBC: Charles River Analytics, Inc.            Topic: MDA13T001

    Missile defense takes place in an uncertain and dynamic environment, so multi-sensor fusion must be employed to aggregate and merge disparate data from the battlefield. However, the fusion process is hindered by the vast amount of uncertainty in operational contexts, such as imprecise measurements and varying environmental conditions. Various algorithms and fusion processes have been developed to ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  8. Adaptive Visualization of Social Networks (ADVIS)

    SBC: PERCEPTRONICS SOLUTIONS, INC.            Topic: ST12A004

    This proposal is to extend into Phase II our development of a new system for Adaptive Visualization of Social Networks (ADVIS). Recent years have seen a dramatic increase in the collection and study of social network data. Numerous social network visualizations have been developed to support user exploration and understanding of these data. However even in the few best systems, cognitive and de ...

    STTR Phase II 2014 Department of DefenseDefense Advanced Research Projects Agency
  9. A Doppler Simulator for Vascular Ultrasound Training

    SBC: Sheehan Medical LLC            Topic: NIBIB

    We will develop and test a simulator of diagnostic vascular ultrasound for use in medical education and professional certification. The simulator will include not only two-dimensional (2D) images but also Doppler spectral waveforms to simulate duplex ultrasound scanning. The rationale is that education in diagnostic ultrasound has traditionally been based on an extended duration of clinical exposu ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Advanced Architectures and Data Exchange Standards for High Performance Computing (HPC) Application to Wide Area Motion Imagery (WAMI) Tracking

    SBC: Lattice Technology Group, Inc.            Topic: AF13AT10

    ABSTRACT: The objective of this effort is to develop next-generation architectural and operational concepts, leveraging recent advances in High Performance Computing (HPC) technologies, to improve Wide Area Motion Imagery (WAMI) tracking capacity and performance. WAMI systems typically produce tens of thousands of moving target indicator (MTI) detections from city-sized urban areas at update rat ...

    STTR Phase I 2014 Department of DefenseAir Force
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