Award Data

PROJECT SUMMARYThe goal of this proposal is to optimize and clinically validate a new diagnostic test for eosinophilic chronic rhinosinusitis (eCRS) at the point-of-care, improving the efficiency, value, and accessibility of personalized medicine. eCRS affects up to 5 million Americans and is characterized by varying degrees of sinonasal and peripheral eosinophilia, linked to treatment responsiven ...

Project Summary and Abstract The most common neurogenic voice disorder is unilateral vocal fold paralysis (UVFP), which can substantially reduce quality of life. Current available surgical treatments offer only temporary improvement in voice through placement of resorbable materials or involve permanent, invasive alteration of the larynx that incompletely restores voice and often requires revision ...

Abstract Currently, clinically used drug abuse medications exist for treatment of addiction to opiates, alcohol, and nicotine, but not psychostimulants, such as methamphetamine (METH). Compounds that co-activate both nociceptin opioid peptide (NOP) and mu receptors have potential for treatment of drug abuse. In particular, buprenorphine, a partial mu agonist/kappa antagonist, which also acts as a ...

  Momentous seeks to deliver a joint health intervention designed specifically for female military servicemembers. It maximizes the benefit of collagen and vitamin C for injury reduction with novel additionals to limit increased injury risk due to the physiological impacsex-specificcific hormones. This effort will adapt the composition of Momentous Collagen Shot, a leading collagen product, to me ...

PROJECT SUMMARY—More than 2 million Americans are hospitalized each year with bone fractures, and many more undergo outpatient procedures for fracture reduction and fixation. Some injuries can be treated with closed reduction and splinting or casting to immobilize the bone during healing. However, at some sites, more than half of fractures require open reduction and internal fixation. Despite ad ...

Composites manufacturing using autoclave cured pre-preg materials is expensive, often size limited, labor intensive, and has slow cycle times limiting production. The AFRL reported the need for improved composite research and demonstrations related to the emerging Advanced Air Mobility market. This project will use novel, out of autoclave composite manufacturing methods including composites based ...

The coordination of manned and unmanned aircraft, artillery, firing lanes, and ground forces can be enhanced by a lane-based approach to asset trajectory planning. In the proposed Phase II STTR effort, we plan to develop an approach, software prototype, simulation, and test and evaluation framework for the coordination of the trajectories of a large number of airborne coalition assets and dynamic ...

Electric vertical take-off and landing (eVTOL) aircrafts are the emerging technology that is expected to revolutionize transportation industry. Agility Prime, a program launched by the Air Force is seeking to accelerate the commercial market for advanced air mobility vehicles. While Li-ion battery is the leading candidate to power these aircrafts, the drawbacks of the battery technology warrant re ...

Summary/Abstract Genomic sequencing is rapidly becoming a standard tool in diagnosing complex diagnostic cases, especially in critically ill newborns, and patients suffering from rare diseases. Current programs focused on addressing these cases utilise a team-based approach to identify, interpret and evaluate a patient’s genetic variants. These diverse teams include bioinformaticians, medical ge ...

Amp Human proposes developing a military-specific adaptation of its Prime Rinse commercial product (itself in mid-stage R&D) that signals the brain ease its regulation of physical performance. As a venture-backed human performance company, Amp Human’s exp