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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Inhibiting Prolyl Hydroxylase to Mimic Natural Acclimatization to High Altitude to Improve Warfighter Performance at High Altitude

    SBC: Research Logistics Company            Topic: SOCOM17C001

    Acclimatization is the long-term adjustment that humans experience when exposed for weeks or months to high altitude. Acclimatization is important in this context because a warfighter who is acclimatized to high altitude is immune to high altitude illness, has superior work capacity, and has cognitive function approaching that found at sea level. In other words, the acclimatized warfighter is opti ...

    STTR Phase I 2018 Department of DefenseSpecial Operations Command
  2. Innovative Mitigation of Radiation Effects in Advanced Technology Nodes

    SBC: Microelectronics Research Development Corporation            Topic: DTRA16A003

    Micro-RDC has developed portable radiation effects test structures that scale to new process nodes.These structures will enable the investigation of the effects of radiation on the new technology from the material processing level as well as the circuit level.Fabricating the chosen structures and the refinement of software to extract the model parameters will be completed in this effort.A suite of ...

    STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
  3. Small Team Command, Control, Communications and Situational Awareness (C3SA), SOCOM08-001

    SBC: CEEBUS TECHNOLOGIES, LLC            Topic: SOCOM08001

    SOF combat swimmers have a need for the continuous monitoring of each others relative position while diving and for the capability of being able to communicate with each other to help establish a common operational picture (COP).The C3SA system was previously developed under SBIR Topic SOCOM08-001 thru the receipt of both Phase I and Phase II SBIR awards.The C3SA established a stand-alone network ...

    STTR Phase II 2018 Department of DefenseSpecial Operations Command
  4. Developing a small peptide to control autoimmune inflammation in type diabetes

    SBC: Op-T-Mune, Inc            Topic: NIAID

    Abstract Type Diabetes T D affects an ever growing population While this disease typically has been associated with juveniles the disease in adult populations is rapidly increasing The defining clinical component is insulin loss which occurs because of sustained inflammation in the islets At present there is no means to prevent or reverse insulin loss A major inflammatory pathway in T D ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. E training of Inmate Peer Caregivers for Enhancing Geriatric and End of life Care in Prisons

    SBC: KLEIN BUENDEL, INC            Topic: NIA

    The US has the highest incarceration rate in the world imprisoning people per The older adult segment of the prison population has more than tripled since and their health issues are common to free people who are years their senior Inmates over the age of have a death rate that is times that of prisoners aged US prison systems are facing sharply increased dema ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Screening for the autoimmune component of multiple sclerosis

    SBC: Op-T-Mune, Inc            Topic: NIAID

    Multiple Sclerosis is an inflammatory neurodegenerative disease with autoimmune components that exacerbate and potentially initiate the disease Diagnosis is invasive time consuming relatively expensive and extremely difficult In fact no clear diagnostic test yet exist A major concern is that MS symptoms are identical to the symptoms of numerous other neurologic diseases OND as well as some ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Non invasive risk assessment tool for pediatric heart failure

    SBC: CORAMIR BIOMEDICAL, INC.            Topic: NHLBI

    ABSTRACT Heart Failure HF in pediatric patients is a devastating disease that is difficult to evaluate even with invasive hospital procedures Importantly and unique to the pediatric population approximately of pediatric HF patients spontaneously recover normal heart function within year of diagnosis Unfortunately there is no reliable clinical parameter or biomarker that allows pedia ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Novel HDAC Inhibitors for Treatment of Hemoglobinopathies

    SBC: CETYA THERAPEUTICS, INC.            Topic: NHLBI

    Project Summary Induction of normal but developmentally silenced fetal globin expression reduces anemia and ameliorates clinical severity in the beta hemoglobinopathies HDACs and are components of the NURD repressor complex which promotes silencing of fetal globin in adult cells Prior generation HDAC inhibitors have increased fetal globin in patients but had limitations for pharmaceu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Clinical Screening Platform for Type Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    Abstract A major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to disease Current criteria involve HLA haplotype and the presence of auto antibodies AA Genome wide associated studies GWAS revealed only immune associated genes including HLA as T D predictors The ability to differentiate from other diseases was very limited Pre type diabetes p T ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Enhancing Care of the Aged and Dying in Prisons

    SBC: KLEIN BUENDEL, INC            Topic: NIA

    The United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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