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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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AI Driven Swarming AUVs
SBC: Certus Core, Inc. Topic: SOCOM22DST01To support Next Generation Intelligence, Surveillance, Reconnaissance, and Situational Awareness applied research goals, Certus Group proposes the deployment of multiple Autonomous Underwater Vehicles (AUVs) in a meshed configuration to enable collaborative autonomous sensing on littoral targets of strategic interest in a GPS denied environment. In order to develop this capability, a number of tec ...
STTR Phase II 2023 Department of DefenseSpecial Operations Command -
Towards intra-operative guidance in brain tumor surgery using real-time resting-state functional MRI
SBC: NeurInsight, LLC Topic: NINDSSummaryResting-state functional MRI (rsfMRI) is a rapidly developing task-free approach for presurgical mapping. It can complement task-based functional MRI (tfMRI) in patients who have difficulties performing tasks and efficiently map resting state networks (RSNs) in regions that are not typically mapped with tfMRI due to time constraints, such as frontal cortex. It has the potential to provide i ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Development of a Novel eNAMPT-Neutralizing mAb for Pulmonary Hypertension
SBC: AQUALUNG THERAPEUTICS, CORP Topic: NHLBIABSTRACT Pulmonary arterial hypertension (PAH) is a fatal disease (without curative therapies) that is critically influenced by dysregulated inflammatory pathways. This A1 R42 Fast Track STTR application focuses on eNAMPT (extra- cellular nicotinamide phosphoribosyltransferase) as a novel, highly attractive PAH target. Aqualung Therapeutics has developed a humanized eNAMPT-neutralizing mAb, ALT-10 ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
A Machine Learning Algorithm to Assess Functional "Brain Age" from an In-Home EEG Sleepband
SBC: NEUROGENECES, INC. Topic: NIA1 PROJECT SUMMARY2 Humans are living longer, resulting in our bodies outliving our brains. Although behavioral changes and better3 management of health conditions can help reverse or slow down premature decline in brain function, pre-4 symptomatic adults are not identified early enough when these changes would make the most significant positive5 impact. Effective intervention requires early detect ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Protection of transplanted heart function by regulation of Na/K pump activity
SBC: WR Biotech, LLC Topic: NHLBIThe objective of this proposal is to examine a novel technique called improved Synchronization Modulation Electric Field (i-SMEF) in the protection of donor hearts and improvement of transplanted graft functions. We will apply the i-SMEF on donor hearts during static cold storage and evaluate the transplanted graft function following heart transplantation in mice.Heart transplantation (HTx) remain ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Image-based risk assessment to identify women at high-risk for breast cancer
SBC: WAVED MEDICAL LLC Topic: NCI7. PROJECT SUMMARY Breast cancer is the most common cancer worldwide and the most common cancer diagnosed in American women. While there has been good progress regarding detection and treatment methods, breast cancer remains the primary cause of death from malignant tumors. Hence, there is a critical need for the development of novel predictive and prognostic factors. Risk assessments are currentl ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of an Educational Product for Accelerating Solutions for Commercialization and Entrepreneurial Development (ASCEND) in Western IDeA States
SBC: NEW MEXICO START-UP FACTORY II LLC Topic: NIGMSProject Summary As a participant in the new IDeA Regional Entrepreneurship Development (I-RED) program, the goal of this proposal is to create an educational product to promote entrepreneurism and commercialization in the Mountain West region of IDeA states. The educational product and overall program are intended to address the needs of IDeA state academic institutions in developing and strengthe ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Human specific STING agonists for the treatment of cancer
SBC: STINGINN, LLC Topic: 102PROJECT SUMMARY Cellular innate immune sensors, such as STING (STIMULATOR OF INTERFERON GENES), have evolved to detect microbial infection of the cell (1-3). STING controls the potent cytosolic DNA-stimulated innate immune pathways and is activated by cyclic dinucleotides (CDNs) such as cyclic di-GMP and cyclic-di-AMP secreted by intracellular bacteria following infection. Alternatively, STING can ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Targeting the eNAMPT/TLR4 pathway to reduce Inflammatory Bowel Disease severity
SBC: AQUALUNG THERAPEUTICS, CORP Topic: 300ABSTRACT Inflammatory bowel disease (IBD) is a debilitating disease (without curative therapies) that is critically influenced by dysregulated inflammatory pathways. This A0 R42 STTR application focuses on a highly novel humanized monoclonal antibody (mAb), ALT-100, to target and neutralize eNAMPT (extracellular nicotinamide phosphoribosyltransferase), a damage-associated molecular pattern protein ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Assessment of Deep Learning Classification Methods for Parkinsonism
SBC: AUTOMATED IMAGING DIAGNOSTICS LLC Topic: 108SUMMARY The growth rate in the number of people diagnosed with Parkinsonism is substantial. Estimates indicate that from 1990 to 2015 the number of Parkinsonism diagnoses doubled, with more than 6 million people currently diagnosed. By 2040, there will be between 12-14 million people diagnosed with Parkinsonism. Parkinson’s disease (PD), multiple system atrophy Parkinsonian variant (MSAp), and p ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health