Award Data

Abstract This project describes the development of NeuroExM™, a highly innovative system for performing comprehensive spatial distribution analysis of populations of messenger RNAs (mRNAs) and proteins in tissue processed for expansion microscopy (ExM)). The groundbreaking technological advantage of ExM, which was recently developed by Dr. Edward S. Boyden (Dept. Biol. Engin., Media Lab and Dept ...

PROJECT SUMMARY Coronary heart disease leading to acute myocardial infarction (MI; heart attack) is a principal cause of mortality worldwide. Cornerstone treatments for MI are designed to restore blood flow (i.e. to “reperfuse”) blocked coronary arteries. Despite reduced times to intervention, and successful stent placement, 30-50% of primary Percutaneous Coronary Intervention (PCI) patients e ...

Abstract This project describes the development of NeuroExM™, a highly innovative system for performing comprehensive spatial distribution analysis of populations of messenger RNAs (mRNAs) and proteins in tissue processed for expansion microscopy (ExM)). The groundbreaking technological advantage of ExM, which was recently developed by Dr. Edward S. Boyden (Dept. Biol. Engin., Media Lab and Dept ...

ABSTRACT The goal of this Fast-Track STTR project is to optimize and test a novel arm restraint in older critically ill mechanically ventilated patients that increases mobility; reduces agitation, use of sedative medications, and delirium; and exhibits high satisfaction and acceptability among hospital staff, family members, and patients. Older mechanically ventilated patients are often immobilize ...

ABSTRACT The goal of this Fast Track STTR project is to optimize and test a novel arm restraint in older critically ill mechanically ventilated patients that increases mobilityreduces agitationuse of sedative medicationsand deliriumand exhibits high satisfaction and acceptability among hospital stafffamily membersand patientsOlder mechanically ventilated patients are often immobilized with wrist r ...

PROJECT SUMMARY ABSTRACT Over a quarter of primary care patients in the United States can be classified as unhealthy drinkers because their alcohol use conveys a high risk of health and social consequences Unfortunately unhealthy drinking is under recognized in spite of the existence of valid screening tools Even when unhealthy drinking is recognized barriers such as provider discomfort shor ...

DESCRIPTION provided by applicant The ultimate goal of this project is to market an electromechanical and software system for Blind and Low Vision B LV individuals that will enable interactive creation communication and printing of Braille annotated tactile graphics In school at home and in the workplace virtually everyone needs to be able to produce a wide variety of freehand sketches ...

DESCRIPTION (provided by applicant): Hip replacement surgery is a tremendously effective and successful treatment for patients suffering from degenerative joint disease. However, revision surgery accounts for about 13% of hip implant surgeries in the U.S.,costing 3 billion annually and presenting significantly increased morbidity and risk of complication for patients. Wear and/or failure of total ...

DESCRIPTION (provided by applicant): The ultimate goal of this project is to market a electromechanical and software system for Blind and Low Vision (B/LV) individuals that will enable creation, communication and reproduction of freehand drawings. In school, at home and in the workplace, virtually everyone needs to be able to produce a wide variety of freehand sketches, diagrams, driving direction ...

DESCRIPTION (provided by applicant): This program will demonstrate the potential for commercial success of a novel approach for tracking and displaying the position and orientation of instruments in image-guided cancer interventions. Prototype systems will be demonstrated in selected pancreatic procedures in human subjects. New clinical applications will be examined and commercialization will beg ...