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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Directed Differentiation of Embryonic Stem Cells using Phage Displayed Ligands

    SBC: OCATA THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to culture human embryonic stem cells generated a great deal of excitement about their vast potential for treating a variety of human diseases such as diabetes, heart disease, neurological, retinal and skin disorders to name a few. Unlike adult stem cells, embryonic stem cells have indefinite growth potential and the potential to develop into any t ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Multi-Organizational Knowledge Based Approach Research

    SBC: 10 BLADE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase 1 STTR project will determine the feasibility of using web services, based on standard SOAP/XML (HL-7) protocols, to exchange Emergency Medical Services (EMS) field data with disparate hospital information systems. It will build upon a pre-hospital software package called iRevive, which consists of a network of wireless, handheld computers linked ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Diffused Optical Tomography using Oxygen-sensitive Luminescent Contrast Agent for

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Molecule specific targeting and improving image contrast have been recognized as important research areas in cancer imaging. Goal of cancer diagnosis and prognosis research is to develop new imaging techniques to detect lesions with certainty in early stages so that they can be treated. Developing biomarkers, which will signal the presence and the type of lesio ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Production of High Specific Activity Lutetium-177

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): A separation method will be tested and evaluated to determine the feasibility of providing no carrier added lutetium-177 (Lu-177) for use in radiotherapeutic applications. An indirect method will be used to produce Lu-177 (neutron capture followed by decay). Separation of the Lu-177 from the target material will enable us to provide carrier-free Lu-177 suita ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. High-Energy Imaging in Support of Radionuclide Therapy

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to design and build cameras that can efficiently detect and image isotopes that have gamma rays with energies that are typically beyond those effectively accessible with conventional cameras. There are no nuclear medicine clinical cameras, today, that combine high efficiency with the ability to image high-energy gamma rays. ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Targeting alpha particle-emitting radionuclides to the nuclei of cancer cells

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal outlines a body of research to evaluate the cytotoxicity and therapeutic efficacy of radiolabeled alpha-melanocyte stimulating hormone (a-MSH) peptide analogs that target a-particle emitting radioisotopes to the nuclei of melanoma cells. The selective targeting of alpha-particle emitting radioisotopes for cancer therapy is emerging as an exciting ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Processing Ac-227 sources for lead-212 and radium-223 required by cancer research

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): NIH sponsored cancer researchers have been obtaining promising results using molecules radiolabeled with lead-212 in treatment for metastatic melanoma and disseminated colon and pancreatic cancers. Another isotope, radium-223 is being used in clinical trials in treatment of skeletal metastases. There is no effective therapy for these diseases. Together 199,280 ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. A Pb-212 Generator Using Resistant Substrate and Rn Cold Trapping

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Targeted Pb-212 therapy in preclinical animal tests has shown a cure in groups receiving the highest dose of this therapy. Scaling the dose that was most efficacious in animal studies to people would bring the human dose required from 50 to 100 mCi. This application will research an approach that would provide a generator system that would support these require ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Nano-Ceramic for Metabolic Stem Cell Engineering

    SBC: Angstrom Medica, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this project is to develop a clinically and commercially viable tissue engineered bone construct using nanocrystalline ceramic scaffolds for proliferating and differentiating adipose-derived progenitor cells into cells of the osteogenic lineage. The use of a nanostructured hydroxyapatite (nano-HAP) scaffold offers several advantages for ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Novel Nanostructured Calcium Phosphate for Gene Delivery to Bone

    SBC: Angstrom Medica, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Osteoporosis is a major and growing health care problem that responds inadequately to standard pharmacologic therapy. Because of its low bone mineral density, osteoporotic bone is mechanically weak and fractures more easily than normal bone. Moreover, fracture repair is compromised in osteoporotic patients. The work described in this Phase I STTR proposal aims ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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