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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Software as a Service Cardiovascular PACS Based on Web 2.0 Technologies

    SBC: HEART IMAGING TECHNOLOGIES, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Nearly two-thirds of all medical imaging procedures in the United States are performed in physician offices, yet few of these small healthcare providers can afford picture archiving and communication systems (PACS) needed to exchange these images with large hospitals. Without online access to previous imaging tests many procedures are repeated, leading to exces ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. CardioPort to Enable Intracardiac Beating Heart and Minimally Invasive Open Heart Surgery

    SBC: Nido Surgical, Inc            Topic: NHLBI

    DESCRIPTIONprovided by applicantThe goal of this Fast Track STTR project is to develop a novel CardioPortTM surgical device that will enable minimally invasive beating heart repair without use of cardiopulmonary bypassCPBThere is a critical unmet need for new instruments to improve the surgical repair of heart defects in childrenCurrent best surgical practices involve either open heart surgery wit ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Developmental Disabilities Dentistry Online

    SBC: Praxis            Topic: NIDCR

    DESCRIPTION (provided by applicant): Individuals with intellectual and developmental disabilities (I/DD) have more untreated caries and a higher prevalence of gingivitis and other periodontal diseases than the general population (NIDCR, 2009). In order to address this health care disparity, more dentists are needed who understand and are trained to meet the needs of this population. Few in-depth ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. DNA helicase and primase inhibitors for biodefense

    SBC: MICROBIOTIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this project is to identify specific inhibitors of B. anthracis helicase and primase and develop them into novel antibiotics for bio-defense. New antibiotics based on novel chemical scaffolds are vital to the bio-defense armory because they are likely to be effective against both natural and engineered resistant forms of bio-terrorist agen ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Cell therapy of diabetes using broad spectrum multipotent stem cells

    SBC: PLUREON CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of insulin-producing cells in many diabetes patients potentially would restore normal glucose homeostasis and prevent the severe long-term complications of the disease. However, the scarcity of donated pancreata currently limits transplantation of the whole organ or of isolated pancreatic islets to a tiny fraction of those patients who might ben ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Developing a Scalable Manufacturing Process for an Oral Bacteriophage Product that Prevents Cholera

    SBC: PhagePro, Inc.            Topic: NIAID

    PROJECT SUMMARY Cholera is an acute and severe disease caused by the bacterium Vibrio cholerae that is spread primarily through contaminated water sources due to a lack of adequate sanitation infrastructure. The World Health Organization estimates that there are at least 3 million cases globally per year, 40 percent of which are spread through household transmission. Current prevention methods req ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Integrated biochemical and bioinformatic technologies for accurate transcriptome-wide full-length RNA assembly.

    SBC: LUCIGEN CORPORATION            Topic: 172

    DESCRIPTION provided by applicant The human transcriptome is significantly more complex than its cognate genome due to the hundreds of thousands of possible isoforms allele specific expression issues variable RNA editing changes and differential expression patterns spanning cell types developmental stages and physiological stresses Next generation sequencing NGS platforms are fundame ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. ASTROCYTE ACTIVATION BY SMALL MOLECULE P2Y1 AGONISTS FOR TREATMENT OF TBI

    SBC: ASTROCYTE PHARMACEUTICALS INC.            Topic: 105

    DESCRIPTION provided by applicant Traumatic brain injuries TBI are an area of significant unmet need with no approved therapeutics and a national burden of $ billion annually Astrocyte Pharmaceuticals is developing a small molecule pharmaceutical agent that would be administered by intravenous injection by emergency responders or a medical professional within hours of injury to limit n ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Multi-Organizational Knowledge Based Approach Research

    SBC: 10 BLADE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase 1 STTR project will determine the feasibility of using web services, based on standard SOAP/XML (HL-7) protocols, to exchange Emergency Medical Services (EMS) field data with disparate hospital information systems. It will build upon a pre-hospital software package called iRevive, which consists of a network of wireless, handheld computers linked ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Novel Class for Opioid Drugs

    SBC: ALGYNOMICS, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): The mu-opioid receptor (MOR) is the primary target for opioid analgesics. While opioids are the most frequently used and effective analgesics for the treatment of moderate to severe clinical pain, their prolonged use leads to reduced efficacy and a number of adverse side effects, including post dosing-induced hyperalgesia and analgesic tolerance. MOR induces an ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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