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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Microfluidic Viral Infection Assay

    SBC: Bellbrook Labs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In less than one year the 1918 Spanish flu pandemic claimed over 20 million lives worldwide, killing 675,000 Americans, more than 10 times the number of deaths to US servicemen in World War I. A similar strain of the vi rus that caused the 1918 pandemic could today kill 2 million Americans and force 10 million to be hospitalized. Although anti-viral drugs are k ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Endoscopically-guided optical coherence tomography for early cancer screening

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal addresses a need for an improved technology for early cancer detection and rapid screening. Recent advances in nanotechnology and high resolution imaging have led to the development of new investigative t ools capable of probing biological tissues at the cellular level. These tools can be used to localize abnormal neoplastic cells and expedite th ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Enhanced Contrast Imaging for Screening of Early Pancreatic Cancer

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal addresses a real need for an improved technology for early detection and rapid screening of ductal pancreatic cancer. Very recent advances in nanotechnology and high resolution optical coherence tomography (OCT) imaging have led to the development of new investigative tools capable of probing biological tissues at the cellular level. These tools ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. A low-cost point-of-care diagnostic test for simultaneous HIV-1 and STI

    SBC: Infoscitex Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): An important approach for HIV/AIDS prevention is to diagnose co-infections that significantly increase the transmission of HIV. In this proposal, we propose to develop a rapid point-of-care (POC) test that simultaneous ly diagnoses HIV-1 and two sexually transmitted infections (STI's). Syphilis and genital herpes are STI's that enhance HIV transmission; if dia ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Botannical Extract Library Screeninig with Human ADAS Cells

    SBC: Zen-Bio, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I STTR proposal has been substantially revised in response to the Study Section review. The proposal was written in response to the NIH Director's newly released roadmap that encourages collaboration betwee n corporate and academic institutions to develop alternative models for conducting research and the suggestion by Dr. Francis Collins, Director ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Fully Compensated Dynamic Shim System for In Vivo MRI and MRS

    SBC: RESONANCE RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Functional MRI, diffusion MRI and MR spectroscopy and spectroscopic imaging have great potential for the study and diagnosis of disease and injury, and guiding surgical therapy. All of these methods benefit greatly fro m the added sensitivity, resolution and contrast from high field strength magnets (3T and above). However, the advantages of higher magnetic fi ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Web-Based Wellness Policy Toolkit for Obesity Prevention in Middle Schools

    SBC: CIRQUE PRODUCTIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Web-Based Wellness Policy Toolkit for Obesity Prevention in Middle Schools The childhood obesity epidemic is escalating with significant adverse health and economic impact. We propose to develop and test a web-based too lkit designed to facilitate implementation of required wellness policies (WP) in middle schools as well as a commercialization strategy for und ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. PRO-Surveyor: Device for Capturing Patient Reported Outcome Data in Children

    SBC: SPECTROCON, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Patient-reported outcomes (PROs) are a component of health-related quality of life that measure aspects of a patient's health that come directly from the patient, typically via the use of valid and reliable que stionnaires. Methods of administration are traditionally paper forms or computerized/internet methods. Each of these current methods has signif ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. A Bioactive Prosthetic Vascular Graft

    SBC: BIOSURFACES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are comprised of either polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Medium (6-8mm) and small (l t5mm) internal diameter (I.D.) prosthetic arterial grafts continue to have unacceptably high failure rates when used in the clinical setting. T ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. The Crystal Optimizer: Kinetic Control of Protein Crystallization

    SBC: RAINDANCE TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Protein crystallization remains a bottleneck in the goal to determine the protein's structure. A microfluidic device denoted the Crystal Optimizer (XOpt) has been developed to optimize the kinetic pathway for the nuclea tion and growth of protein crystals once the lead conditions have been identified by other screening methods. The device drives each of hundred ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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