Award Data

"Three-dimensional textile reinforcement architectures with straight in-plane fibers and optimized through thickness fiber content are considered as efficient solutions for the next generation of light weight, damage tolerant, high strength compositesallowing for cost-effective manufacturing solutions. The 3-D weaving process is gentle to the fibers, thus making automated fiber optic sensor insert ...

Basic research aimed at understanding the complex regulations and interactions lead to various diseases requires novel bioanalytical approaches that allow detailed characterization of the proteome with ultra high-speed and sensitivity so that important regulatory proteins can be effectively studied. For the analysis of complex protein mixtures such as cell lysates, two-dimensional polyacrylamide g ...

DESCRIPTION (provided by investigator): This application seeks Phase II funding to continue the development of the Elementary School Success Profile (ESSP) Drug Abuse Prevention Sreening Tool. The long-term objective is to help school-based health and mental health professionals quickly and accurately assess students' risk and protective factor status for adolescent substance use and other harmfu ...

We propose to further develop a new technique for imaging underground facilities based on the passive monitoring of acoustic emissions from both stationary and moving equipment within such facilities. It is well known that all mechanical devices, such asmotors, gears, etc, emit acoustic signals. It is possible to identify an acoustic source based on its noise spectrum. During Phase I, we have demo ...

DESCRIPTION (provided by applicant): Pretest probability assessment (PTP) plays a pivotal role in the evaluation of pulmonary embolism (PE) in the emergency department (ED) and accurate PTP assessment can modify defensive test-ordering behavior by physicians. However, current methods of PTP assessment produce broad categories of risk that tend to over fit individual patients and seldom obviate tes ...

DESCRIPTION (provided by applicant): The Genomics Revolution and the resultant explosion of knowledge in genomics are shaping our futures. Therefore, it is crucial that knowledge of genomics is broadly disseminated, so that future scientists, educators, policy makers, community leaders, and heads of households can harness the beneficial power of genomic science. Given the indiscriminate impact of ...

DESCRIPTION (provided by applicant): The purpose of this Phase II STTR is to complete the development of a web-based training system, the All Stars Online Community. This system is designed to improve teachers' delivery of All Stars, an adolescent substance use prevention program. The goal of training is to help teachers advance in their teaching skills and understanding of underlying preventi ...

Three-dimensional woven and braided fiber architectures provide important advantages to composites, including suppression of delamination, high damage tolerance, improved through-the-thickness properties, simplicity and cost-effectiveness of manufacturing complex composite structural components. However, in order to diversify applications and reach high volumes of utilization of these materials in ...

DESCRIPTION (provided by applicant): Adolescent drug use continues to be a major public health problem. The need for late onset drug prevention and early cessation in high schools is great, yet few universal programs exist that target alcohol, tobacco, and other drug use among high school students. Crossroads is a universal drug prevention program based on a cooperative relationship between high s ...

DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of a defective gene rather than, as commonly practiced, to inhibit the expression of an undesirable ge ...