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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Programming Metabolically Fit TILs for Immunotherapy

    SBC: LIPO-IMMUNO TECH LLC            Topic: NCI

    ABSTRACT Advances in molecular biology and genetic engineering have led to the design and use of modified T cells recognize tumors to achieve significant tumor control upon adoptive cell transfer (ACT) to patients. These T cells are either transduced with tumor antigen reactive T cell receptors (TCR), or chimeric antigen receptors (CARs). Recently, a surge in studies with neo-antigen reactive T ce ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Zero Trust Methodology for Digital Modeling

    SBC: ISTARI, INC.            Topic: X22DOTCSO1

    At a high level, the major mission focus of this research is:  How can the DAF and broader DoD leverage Zero Trust methodology into digital model sharing and collaboration? The technical focus of this research is:  What is the best manner to link digital

    STTR Phase II 2023 Department of DefenseAir Force
  3. Fast-Response Event-Based Image Sensor and Camera

    SBC: ALPHACORE INC            Topic: X22DOTCSO1

    Event-based cameras are novel sensors that output brightness changes in the form of a stream of asynchronous "events" instead of intensity frames. Compared to conventional image sensors, they offer significant advantages: high temporal resolution, high dy

    STTR Phase II 2023 Department of DefenseAir Force
  4. Ultra-Broadband and High Average Power Directional IR Countermeasures

    SBC: Applied Energetics, Inc.            Topic: A21CT018

    High intensity light sources can be effectively used for Infrared Countermeasures (IRCM) against Electrooptic (EO) based systems. The operational requirements for an IRCM optical source depend upon the desired effects along with engagement parameters such as range, atmospheric conditions, engagement geometry, target characteristics, and IRCM platform constraints. Of interest, are systems that can ...

    STTR Phase II 2023 Department of DefenseArmy
  5. SeaCraft/AeroNautical Data-collector (SCAND) for real-time target recognition

    SBC: HYDRONALIX INC            Topic: SOCOM22DST01

    Artificial intelligence-assisted detection and imaging technology can gather data on underwater, surface, and aerial threats to gain situational awareness over opposing forces, and aids in navigating dangerous marine and terrestrial environments. Successful and efficient use of intel is crucial for strategic information warfare, but many current technologies require active monitoring to identify t ...

    STTR Phase II 2023 Department of DefenseSpecial Operations Command
  6. Development of SP-A Derived Peptidomimetics for the Treatment of Asthma- Phase II

    SBC: RaeSedo, LLC            Topic: NHLBI

    Current treatments for asthma, while reducing exacerbations in a subset of patients by focusing on airway inflammation, do not eliminate them. Asthma exacerbations are a significant cause of morbidity and mortality in asthma as they can lead to airway injury, lung function decline and death. Exacerbations in more severe asthmatics are of particular concern, as health care costs and lost productivi ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Critical angle reflection imaging for label-free quantification of molecular interactions

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    TITLE: Critical angle reflection imaging (CARi) for label-free quantification of molecular interactions SUMMARYMeasuring molecular interactions of proteins are critical for understanding protein functions and cellular processes, for discovery and validating biomarkers, and for developing and screening drugs. In particular, membrane proteins play key roles in many cellular functions and are the lar ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Affordable sialoglycans and associated reagents for expanded chemoenzymatic production

    SBC: Integrated Micro-Chromatography Systems, Inc.            Topic: 300

    Project Summary Sialoglycans are sialic acid-containing oligosaccharides that play important biological roles in human biology and pathology and are indispensable molecular probes for research related to bacterial and viral infection, cancer metastasis, immune regulation, etc. The multifaceted functions of sialoglycans in human milk are also being explored. Nevertheless, sialoglycan-related resear ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Discrete Event System Specification (DEVS)-based virtual as is simulation test platform (DVAST)

    SBC: RTSYNC CORP            Topic: MDA20T002

    In Phase I, the RTSync team investigated the design of a non-real-time simulation platform that created an opportunity to radically change the way simulation utilizing enterprises include high fidelity models of software systems within their simulations. The new approach to developing and testing proposed System of System (SoS) architectures is to employ models of hardware systems that execute the ...

    STTR Phase II 2022 Department of DefenseMissile Defense Agency
  10. LIMPET- Lightweight Modular Perception Enhancement

    SBC: KATALYST SPACE TECHNOLOGIES, LLC            Topic: AF20CTCSO1

    The United States Space Force has identified Space Domain Awareness (SDA) as a critical mission domain to ensure domestic space superiority. Threats posed by passive debris and active counter-space assets are rapidly evolving. Katalyst proposes a follow-o

    STTR Phase II 2022 Department of DefenseAir Force
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